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Adipose triglyceride lipase contributes to cancer-associated cachexia.
Das SK, Eder S, Schauer S, Diwoky C, Temmel H, Guertl B, Gorkiewicz G, Tamilarasan KP, Kumari P, Trauner M, Zimmermann R, Vesely P, Haemmerle G, Zechner R, Hoefler G. Das SK, et al. Among authors: trauner m. Science. 2011 Jul 8;333(6039):233-8. doi: 10.1126/science.1198973. Epub 2011 Jun 16. Science. 2011. PMID: 21680814
Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemia.
Kratzer A, Buchebner M, Pfeifer T, Becker TM, Uray G, Miyazaki M, Miyazaki-Anzai S, Ebner B, Chandak PG, Kadam RS, Calayir E, Rathke N, Ahammer H, Radovic B, Trauner M, Hoefler G, Kompella UB, Fauler G, Levi M, Levak-Frank S, Kostner GM, Kratky D. Kratzer A, et al. Among authors: trauner m. J Lipid Res. 2009 Feb;50(2):312-26. doi: 10.1194/jlr.M800376-JLR200. Epub 2008 Sep 23. J Lipid Res. 2009. PMID: 18812595 Free PMC article.
ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1.
Haemmerle G, Moustafa T, Woelkart G, Büttner S, Schmidt A, van de Weijer T, Hesselink M, Jaeger D, Kienesberger PC, Zierler K, Schreiber R, Eichmann T, Kolb D, Kotzbeck P, Schweiger M, Kumari M, Eder S, Schoiswohl G, Wongsiriroj N, Pollak NM, Radner FP, Preiss-Landl K, Kolbe T, Rülicke T, Pieske B, Trauner M, Lass A, Zimmermann R, Hoefler G, Cinti S, Kershaw EE, Schrauwen P, Madeo F, Mayer B, Zechner R. Haemmerle G, et al. Among authors: trauner m. Nat Med. 2011 Aug 21;17(9):1076-85. doi: 10.1038/nm.2439. Nat Med. 2011. PMID: 21857651 Free PMC article.
Alterations in lipid metabolism mediate inflammation, fibrosis, and proliferation in a mouse model of chronic cholestatic liver injury.
Moustafa T, Fickert P, Magnes C, Guelly C, Thueringer A, Frank S, Kratky D, Sattler W, Reicher H, Sinner F, Gumhold J, Silbert D, Fauler G, Höfler G, Lass A, Zechner R, Trauner M. Moustafa T, et al. Among authors: trauner m. Gastroenterology. 2012 Jan;142(1):140-151.e12. doi: 10.1053/j.gastro.2011.09.051. Epub 2011 Oct 14. Gastroenterology. 2012. PMID: 22001865
Lack of monoacylglycerol lipase prevents hepatic steatosis by favoring lipid storage in adipose tissue and intestinal malabsorption.
Tardelli M, Bruschi FV, Claudel T, Fuchs CD, Auer N, Kunczer V, Stojakovic T, Scharnagl H, Habib A, Grabner GF, Zimmermann R, Lotersztajn S, Trauner M. Tardelli M, et al. Among authors: trauner m. J Lipid Res. 2019 Jul;60(7):1284-1292. doi: 10.1194/jlr.M093369. Epub 2019 May 2. J Lipid Res. 2019. PMID: 31048404 Free PMC article.
777 results