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Modulating native GABAA receptors in medulloblastoma with positive allosteric benzodiazepine-derivatives induces cell death.
Kallay L, Keskin H, Ross A, Rupji M, Moody OA, Wang X, Li G, Ahmed T, Rashid F, Stephen MR, Cottrill KA, Nuckols TA, Xu M, Martinson DE, Tranghese F, Pei Y, Cook JM, Kowalski J, Taylor MD, Jenkins A, Pomeranz Krummel DA, Sengupta S. Kallay L, et al. Among authors: tranghese f. J Neurooncol. 2019 May;142(3):411-422. doi: 10.1007/s11060-019-03115-0. Epub 2019 Feb 6. J Neurooncol. 2019. PMID: 30725256 Free PMC article.
First In Vivo Testing of Compounds Targeting Group 3 Medulloblastomas Using an Implantable Microdevice as a New Paradigm for Drug Development.
Jonas O, Calligaris D, Methuku KR, Poe MM, Francois JP, Tranghese F, Changelian A, Sieghart W, Ernst M, Krummel DA, Cook JM, Pomeroy SL, Cima M, Agar NY, Langer R, Sengupta S. Jonas O, et al. Among authors: tranghese f. J Biomed Nanotechnol. 2016 Jun;12(6):1297-302. doi: 10.1166/jbn.2016.2262. J Biomed Nanotechnol. 2016. PMID: 27319222 Free PMC article.