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BECLIN1 is essential for intestinal homeostasis involving autophagy-independent mechanisms through its function in endocytic trafficking.
Tran S, Juliani J, Harris TJ, Evangelista M, Ratcliffe J, Ellis SL, Baloyan D, Reehorst CM, Nightingale R, Luk IY, Jenkins LJ, Ghilas S, Yakou MH, Inguanti C, Johnson C, Buchert M, Lee JC, De Cruz P, Duszyc K, Gleeson PA, Kile BT, Mielke LA, Yap AS, Mariadason JM, Douglas Fairlie W, Lee EF. Tran S, et al. Commun Biol. 2024 Feb 20;7(1):209. doi: 10.1038/s42003-024-05890-7. Commun Biol. 2024. PMID: 38378743 Free PMC article.
Crosstalk between apoptosis and autophagy signaling pathways.
Fairlie WD, Tran S, Lee EF. Fairlie WD, et al. Among authors: tran s. Int Rev Cell Mol Biol. 2020;352:115-158. doi: 10.1016/bs.ircmb.2020.01.003. Epub 2020 Feb 5. Int Rev Cell Mol Biol. 2020. PMID: 32334814 Review.
Diversity in the intrinsic apoptosis pathway of nematodes.
Young ND, Harris TJ, Evangelista M, Tran S, Wouters MA, Soares da Costa TP, Kershaw NJ, Gasser RB, Smith BJ, Lee EF, Fairlie WD. Young ND, et al. Among authors: tran s. Commun Biol. 2020 Aug 28;3(1):478. doi: 10.1038/s42003-020-01208-5. Commun Biol. 2020. PMID: 32859965 Free PMC article.
Structural insights into BCL2 pro-survival protein interactions with the key autophagy regulator BECN1 following phosphorylation by STK4/MST1.
Lee EF, Smith NA, Soares da Costa TP, Meftahi N, Yao S, Harris TJ, Tran S, Pettikiriarachchi A, Perugini MA, Keizer DW, Evangelista M, Smith BJ, Fairlie WD. Lee EF, et al. Among authors: tran s. Autophagy. 2019 May;15(5):785-795. doi: 10.1080/15548627.2018.1564557. Epub 2019 Jan 9. Autophagy. 2019. PMID: 30626284 Free PMC article.
Genotype-Tailored ERK/MAPK Pathway and HDAC Inhibition Rewires the Apoptotic Rheostat to Trigger Colorectal Cancer Cell Death.
Jenkins LJ, Luk IY, Fairlie WD, Lee EF, Palmieri M, Schoffer KL, Tan T, Ng I, Vukelic N, Tran S, Tse JWT, Nightingale R, Alam Z, Chionh F, Iatropoulos G, Ernst M, Afshar-Sterle S, Desai J, Gibbs P, Sieber OM, Dhillon AS, Tebbutt NC, Mariadason JM. Jenkins LJ, et al. Among authors: tran s. Mol Cancer Ther. 2023 Jan 3;22(1):52-62. doi: 10.1158/1535-7163.MCT-22-0101. Mol Cancer Ther. 2023. PMID: 36343387 Free PMC article.
BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival.
Lee EF, Harris TJ, Tran S, Evangelista M, Arulananda S, John T, Ramnac C, Hobbs C, Zhu H, Gunasingh G, Segal D, Behren A, Cebon J, Dobrovic A, Mariadason JM, Strasser A, Rohrbeck L, Haass NK, Herold MJ, Fairlie WD. Lee EF, et al. Among authors: tran s. Cell Death Dis. 2019 Apr 24;10(5):342. doi: 10.1038/s41419-019-1568-3. Cell Death Dis. 2019. PMID: 31019203 Free PMC article.
Every minute matters: Improving outcomes for penetrating trauma through prehospital advanced resuscitative care.
Duchesne J, McLafferty BJ, Broome JM, Caputo S, Ritondale JP, Tatum D, Taghavi S, Jackson-Weaver O, Tran S, McGrew P, Harrell KN, Smith A, Nichols E, Dransfield T, Marino M, Piehl M. Duchesne J, et al. Among authors: tran s. J Trauma Acute Care Surg. 2024 May 1. doi: 10.1097/TA.0000000000004363. Online ahead of print. J Trauma Acute Care Surg. 2024. PMID: 38689386
984 results