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Prediction of site-specific interactions in antibody-antigen complexes: the proABC method and server.
Olimpieri PP, Chailyan A, Tramontano A, Marcatili P. Olimpieri PP, et al. Among authors: tramontano a. Bioinformatics. 2013 Sep 15;29(18):2285-91. doi: 10.1093/bioinformatics/btt369. Epub 2013 Jun 26. Bioinformatics. 2013. PMID: 23803466 Free PMC article.
RESULTS: In this article, we present a method to identify, on the basis of the antibody sequence alone, which residues of an antibody directly interact with its cognate antigen. The method, based on the random forest automatic learning techniques, reaches a recall a …
RESULTS: In this article, we present a method to identify, on the basis of the antibody sequence alone, which residues of an antibody …
The MoVIN server for the analysis of protein interaction networks.
Marcatili P, Bussotti G, Tramontano A. Marcatili P, et al. Among authors: tramontano a. BMC Bioinformatics. 2008 Mar 26;9 Suppl 2(Suppl 2):S11. doi: 10.1186/1471-2105-9-S2-S11. BMC Bioinformatics. 2008. PMID: 18387199 Free PMC article.
PIGS: automatic prediction of antibody structures.
Marcatili P, Rosi A, Tramontano A. Marcatili P, et al. Among authors: tramontano a. Bioinformatics. 2008 Sep 1;24(17):1953-4. doi: 10.1093/bioinformatics/btn341. Epub 2008 Jul 19. Bioinformatics. 2008. PMID: 18641403
PICMI: mapping point mutations on genomes.
Le Pera L, Marcatili P, Tramontano A. Le Pera L, et al. Among authors: tramontano a. Bioinformatics. 2010 Nov 15;26(22):2904-5. doi: 10.1093/bioinformatics/btq547. Epub 2010 Oct 12. Bioinformatics. 2010. PMID: 20940168 Free PMC article.
Tabhu: tools for antibody humanization.
Olimpieri PP, Marcatili P, Tramontano A. Olimpieri PP, et al. Among authors: tramontano a. Bioinformatics. 2015 Feb 1;31(3):434-5. doi: 10.1093/bioinformatics/btu667. Epub 2014 Oct 9. Bioinformatics. 2015. PMID: 25304777 Free PMC article.
Antibody humanization methods are designed to produce molecules with a better safety profile still maintaining their ability to bind the antigen. This can be accomplished by grafting the non-human regions determining the antigen specificity into a suitable human tem …
Antibody humanization methods are designed to produce molecules with a better safety profile still maintaining their ability to bind …
PIGSPro: prediction of immunoGlobulin structures v2.
Lepore R, Olimpieri PP, Messih MA, Tramontano A. Lepore R, et al. Among authors: tramontano a. Nucleic Acids Res. 2017 Jul 3;45(W1):W17-W23. doi: 10.1093/nar/gkx334. Nucleic Acids Res. 2017. PMID: 28472367 Free PMC article.
383 results