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Accelerating development of high-risk neuroblastoma patient-derived xenograft models for preclinical testing and personalised therapy.
Kamili A, Gifford AJ, Li N, Mayoh C, Chow SO, Failes TW, Eden GL, Cadiz R, Xie J, Lukeis RE, Norris MD, Haber M, McCowage GB, Arndt GM, Trahair TN, Fletcher JI. Kamili A, et al. Among authors: trahair tn. Br J Cancer. 2020 Mar;122(5):680-691. doi: 10.1038/s41416-019-0682-4. Epub 2020 Jan 10. Br J Cancer. 2020. PMID: 31919402 Free PMC article.
Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects.
Marshall GM, Gherardi S, Xu N, Neiron Z, Trahair T, Scarlett CJ, Chang DK, Liu PY, Jankowski K, Iraci N, Haber M, Norris MD, Keating J, Sekyere E, Jonquieres G, Stossi F, Katzenellenbogen BS, Biankin AV, Perini G, Liu T. Marshall GM, et al. Oncogene. 2010 Nov 4;29(44):5957-68. doi: 10.1038/onc.2010.332. Epub 2010 Aug 9. Oncogene. 2010. PMID: 20697349
SIRT1 promotes N-Myc oncogenesis through a positive feedback loop involving the effects of MKP3 and ERK on N-Myc protein stability.
Marshall GM, Liu PY, Gherardi S, Scarlett CJ, Bedalov A, Xu N, Iraci N, Valli E, Ling D, Thomas W, van Bekkum M, Sekyere E, Jankowski K, Trahair T, Mackenzie KL, Haber M, Norris MD, Biankin AV, Perini G, Liu T. Marshall GM, et al. PLoS Genet. 2011 Jun;7(6):e1002135. doi: 10.1371/journal.pgen.1002135. Epub 2011 Jun 16. PLoS Genet. 2011. PMID: 21698133 Free PMC article.
Direct effects of Bmi1 on p53 protein stability inactivates oncoprotein stress responses in embryonal cancer precursor cells at tumor initiation.
Calao M, Sekyere EO, Cui HJ, Cheung BB, Thomas WD, Keating J, Chen JB, Raif A, Jankowski K, Davies NP, Bekkum MV, Chen B, Tan O, Ellis T, Norris MD, Haber M, Kim ES, Shohet JM, Trahair TN, Liu T, Wainwright BJ, Ding HF, Marshall GM. Calao M, et al. Among authors: trahair tn. Oncogene. 2013 Aug 1;32(31):3616-26. doi: 10.1038/onc.2012.368. Epub 2012 Aug 20. Oncogene. 2013. PMID: 22907436
Reply: Comment on 'Beta-blockers increase response to chemotherapy via direct anti-tumour and anti-angiogenic mechanisms in neuroblastoma'--β-blockers are potent anti-angiogenic and chemo-sensitising agents, rather than cytotoxic drugs.
Pasquier E, Andre N, Trahair T, Kavallaris M. Pasquier E, et al. Br J Cancer. 2013 Oct 1;109(7):2024-5. doi: 10.1038/bjc.2013.498. Epub 2013 Aug 22. Br J Cancer. 2013. PMID: 23969728 Free PMC article. No abstract available.
Identification of plasma complement C3 as a potential biomarker for neuroblastoma using a quantitative proteomic approach.
Kim PY, Tan O, Diakiw SM, Carter D, Sekerye EO, Wasinger VC, Liu T, Kavallaris M, Norris MD, Haber M, Chesler L, Dolnikov A, Trahair TN, Cheung NK, Marshall GM, Cheung BB. Kim PY, et al. Among authors: trahair tn. J Proteomics. 2014 Jan 16;96:1-12. doi: 10.1016/j.jprot.2013.10.032. Epub 2013 Nov 4. J Proteomics. 2014. PMID: 24200836 Free article. Clinical Trial.
Persistent MRD before and after allogeneic BMT predicts relapse in children with acute lymphoblastic leukaemia.
Sutton R, Shaw PJ, Venn NC, Law T, Dissanayake A, Kilo T, Haber M, Norris MD, Fraser C, Alvaro F, Revesz T, Trahair TN, Dalla-Pozza L, Marshall GM, O'Brien TA. Sutton R, et al. Among authors: trahair tn. Br J Haematol. 2015 Feb;168(3):395-404. doi: 10.1111/bjh.13142. Epub 2014 Oct 14. Br J Haematol. 2015. PMID: 25312094 Free article. Clinical Trial.
94 results