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Page 1
Challenges in IBD Research: Preclinical Human IBD Mechanisms.
Pizarro TT, Stappenbeck TS, Rieder F, Rosen MJ, Colombel JF, Donowitz M, Towne J, Mazmanian SK, Faith JJ, Hodin RA, Garrett WS, Fichera A, Poritz LS, Cortes CJ, Shtraizent N, Honig G, Snapper SB, Hurtado-Lorenzo A, Salzman NH, Chang EB. Pizarro TT, et al. Among authors: towne j. Inflamm Bowel Dis. 2019 May 16;25(Suppl 2):S5-S12. doi: 10.1093/ibd/izz075. Inflamm Bowel Dis. 2019. PMID: 31095706 Review.
Low-Dose Interleukin-2 Ameliorates Colitis in a Preclinical Humanized Mouse Model.
Goettel JA, Kotlarz D, Emani R, Canavan JB, Konnikova L, Illig D, Frei SM, Field M, Kowalik M, Peng K, Gringauz J, Mitsialis V, Wall SM, Tsou A, Griffith AE, Huang Y, Friedman JR, Towne JE, Plevy SE, O'Hara Hall A, Snapper SB. Goettel JA, et al. Among authors: towne je. Cell Mol Gastroenterol Hepatol. 2019;8(2):193-195. doi: 10.1016/j.jcmgh.2019.05.001. Epub 2019 May 9. Cell Mol Gastroenterol Hepatol. 2019. PMID: 31078723 Free PMC article. No abstract available.
Abnormal Small Intestinal Epithelial Microvilli in Patients With Crohn's Disease.
VanDussen KL, Stojmirović A, Li K, Liu TC, Kimes PK, Muegge BD, Simpson KF, Ciorba MA, Perrigoue JG, Friedman JR, Towne JE, Head RD, Stappenbeck TS. VanDussen KL, et al. Gastroenterology. 2018 Sep;155(3):815-828. doi: 10.1053/j.gastro.2018.05.028. Epub 2018 May 18. Gastroenterology. 2018. PMID: 29782846 Free PMC article.
A Role for IL-12 in IBD after All?
Greving CNA, Towne JE. Greving CNA, et al. Immunity. 2019 Aug 20;51(2):209-211. doi: 10.1016/j.immuni.2019.07.008. Immunity. 2019. PMID: 31433967 Free article.
The CSF-1-receptor inhibitor, JNJ-40346527 (PRV-6527), reduced inflammatory macrophage recruitment to the intestinal mucosa and suppressed murine T cell mediated colitis.
Manthey CL, Moore BA, Chen Y, Loza MJ, Yao X, Liu H, Belkowski SM, Raymond-Parks H, Dunford PJ, Leon F, Towne JE, Plevy SE. Manthey CL, et al. Among authors: towne je. PLoS One. 2019 Nov 11;14(11):e0223918. doi: 10.1371/journal.pone.0223918. eCollection 2019. PLoS One. 2019. PMID: 31710624 Free PMC article.
Differing roles for short chain fatty acids and GPR43 agonism in the regulation of intestinal barrier function and immune responses.
D'Souza WN, Douangpanya J, Mu S, Jaeckel P, Zhang M, Maxwell JR, Rottman JB, Labitzke K, Willee A, Beckmann H, Wang Y, Li Y, Schwandner R, Johnston JA, Towne JE, Hsu H. D'Souza WN, et al. Among authors: towne je. PLoS One. 2017 Jul 20;12(7):e0180190. doi: 10.1371/journal.pone.0180190. eCollection 2017. PLoS One. 2017. PMID: 28727837 Free PMC article.
Get the IL-17F outta here!
Hall AO, Towne JE, Plevy SE. Hall AO, et al. Nat Immunol. 2018 Jul;19(7):648-650. doi: 10.1038/s41590-018-0141-z. Nat Immunol. 2018. PMID: 29915294 No abstract available.
283 results