Tower RJ - Search Results

1

Neuron-to-vessel signaling is a required feature of aberrant stem cell commitment after soft tissue trauma.

Qin Q, Gomez-Salazar M, Cherief M, Pagani CA, Lee S, Hwang C, Tower RJ, Onggo S, Sun Y, Piplani A, Li Z, Ramesh S, Clemens TL, Levi B, James AW. Qin Q, et al. Among authors: tower rj. Bone Res. 2022 Jun 1;10(1):43. doi: 10.1038/s41413-022-00216-x. Bone Res. 2022. PMID: 35641477 Free PMC article.

2

Vhl deletion in osteoblasts boosts cellular glycolysis and improves global glucose metabolism.

Dirckx N, Tower RJ, Mercken EM, Vangoitsenhoven R, Moreau-Triby C, Breugelmans T, Nefyodova E, Cardoen R, Mathieu C, Van der Schueren B, Confavreux CB, Clemens TL, Maes C. Dirckx N, et al. Among authors: tower rj. J Clin Invest. 2018 Mar 1;128(3):1087-1105. doi: 10.1172/JCI97794. Epub 2018 Feb 12. J Clin Invest. 2018. PMID: 29431735 Free PMC article.

3

Comparison of skeletal and soft tissue pericytes identifies CXCR4⁺ bone forming mural cells in human tissues.

Xu J, Li D, Hsu CY, Tian Y, Zhang L, Wang Y, Tower RJ, Chang L, Meyers CA, Gao Y, Broderick K, Morris C, Hooper JE, Nimmagadda S, Péault B, James AW. Xu J, et al. Among authors: tower rj. Bone Res. 2020 May 22;8(1):22. doi: 10.1038/s41413-020-0097-0. eCollection 2020. Bone Res. 2020. PMID: 32509378 Free PMC article.

4

Lysosomal protein surface expression discriminates fat- from bone-forming human mesenchymal precursor cells.

Xu J, Wang Y, Hsu CY, Negri S, Tower RJ, Gao Y, Tian Y, Sono T, Meyers CA, Hardy WR, Chang L, Hu S, Kahn N, Broderick K, Péault B, James AW. Xu J, et al. Among authors: tower rj. Elife. 2020 Oct 12;9:e58990. doi: 10.7554/eLife.58990. Elife. 2020. PMID: 33044169 Free PMC article.

5

Systemic DKK1 neutralization enhances human adipose-derived stem cell mediated bone repair.

Negri S, Wang Y, Sono T, Qin Q, Hsu GC, Cherief M, Xu J, Lee S, Tower RJ, Yu V, Piplani A, Meyers CA, Broderick K, Lee M, James AW. Negri S, et al. Among authors: tower rj. Stem Cells Transl Med. 2021 Apr;10(4):610-622. doi: 10.1002/sctm.20-0293. Epub 2020 Dec 30. Stem Cells Transl Med. 2021. PMID: 33377628 Free PMC article.

6

Genomic variants within chromosome 14q32.32 regulate bone mass through MARK3 signaling in osteoblasts.

Zhang Q, Mesner LD, Calabrese GM, Dirckx N, Li Z, Verardo A, Yang Q, Tower RJ, Faugere MC, Farber CR, Clemens TL. Zhang Q, et al. Among authors: tower rj. J Clin Invest. 2021 Apr 1;131(7):e142580. doi: 10.1172/JCI142580. J Clin Invest. 2021. PMID: 33792563 Free PMC article.

7

NGF-TrkA signaling dictates neural ingrowth and aberrant osteochondral differentiation after soft tissue trauma.

Lee S, Hwang C, Marini S, Tower RJ, Qin Q, Negri S, Pagani CA, Sun Y, Stepien DM, Sorkin M, Kubiak CA, Visser ND, Meyers CA, Wang Y, Rasheed HA, Xu J, Miller S, Huber AK, Minichiello L, Cederna PS, Kemp SWP, Clemens TL, James AW, Levi B. Lee S, et al. Among authors: tower rj. Nat Commun. 2021 Aug 16;12(1):4939. doi: 10.1038/s41467-021-25143-z. Nat Commun. 2021. PMID: 34400627 Free PMC article.

8

Spatial transcriptomics reveals a role for sensory nerves in preserving cranial suture patency through modulation of BMP/TGF-β signaling.

Tower RJ, Li Z, Cheng YH, Wang XW, Rajbhandari L, Zhang Q, Negri S, Uytingco CR, Venkatesan A, Zhou FQ, Cahan P, James AW, Clemens TL. Tower RJ, et al. Proc Natl Acad Sci U S A. 2021 Oct 19;118(42):e2103087118. doi: 10.1073/pnas.2103087118. Proc Natl Acad Sci U S A. 2021. PMID: 34663698 Free PMC article.

9

PDGFRα reporter activity identifies periosteal progenitor cells critical for bone formation and fracture repair.

Xu J, Wang Y, Li Z, Tian Y, Li Z, Lu A, Hsu CY, Negri S, Tang C, Tower RJ, Morris C, James AW. Xu J, et al. Among authors: tower rj. Bone Res. 2022 Jan 25;10(1):7. doi: 10.1038/s41413-021-00176-8. Bone Res. 2022. PMID: 35075130 Free PMC article.

10

NGF-p75 signaling coordinates skeletal cell migration during bone repair.

Xu J, Li Z, Tower RJ, Negri S, Wang Y, Meyers CA, Sono T, Qin Q, Lu A, Xing X, McCarthy EF, Clemens TL, James AW. Xu J, et al. Among authors: tower rj. Sci Adv. 2022 Mar 18;8(11):eabl5716. doi: 10.1126/sciadv.abl5716. Epub 2022 Mar 18. Sci Adv. 2022. PMID: 35302859 Free PMC article.

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