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Caveolin-1 controls mitochondrial damage and ROS production by regulating fission - fusion dynamics and mitophagy.
Jiang Y, Krantz S, Qin X, Li S, Gunasekara H, Kim YM, Zimnicka A, Bae M, Ma K, Toth PT, Hu Y, Shajahan-Haq AN, Patel HH, Gentile S, Bonini MG, Rehman J, Liu Y, Minshall RD. Jiang Y, et al. Among authors: toth pt. Redox Biol. 2022 Jun;52:102304. doi: 10.1016/j.redox.2022.102304. Epub 2022 Apr 6. Redox Biol. 2022. PMID: 35413643 Free PMC article.
Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension.
Marsboom G, Toth PT, Ryan JJ, Hong Z, Wu X, Fang YH, Thenappan T, Piao L, Zhang HJ, Pogoriler J, Chen Y, Morrow E, Weir EK, Rehman J, Archer SL. Marsboom G, et al. Among authors: toth pt. Circ Res. 2012 May 25;110(11):1484-97. doi: 10.1161/CIRCRESAHA.111.263848. Epub 2012 Apr 17. Circ Res. 2012. PMID: 22511751 Free PMC article.
Flk1+ and VE-cadherin+ endothelial cells derived from iPSCs recapitulates vascular development during differentiation and display similar angiogenic potential as ESC-derived cells.
Kohler EE, Wary KK, Li F, Chatterjee I, Urao N, Toth PT, Ushio-Fukai M, Rehman J, Park C, Malik AB. Kohler EE, et al. Among authors: toth pt. PLoS One. 2013 Dec 30;8(12):e85549. doi: 10.1371/journal.pone.0085549. eCollection 2013. PLoS One. 2013. PMID: 24386480 Free PMC article.
Hyperoxia-induced p47phox activation and ROS generation is mediated through S1P transporter Spns2, and S1P/S1P1&2 signaling axis in lung endothelium.
Harijith A, Pendyala S, Ebenezer DL, Ha AW, Fu P, Wang YT, Ma K, Toth PT, Berdyshev EV, Kanteti P, Natarajan V. Harijith A, et al. Among authors: toth pt. Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L337-51. doi: 10.1152/ajplung.00447.2015. Epub 2016 Jun 24. Am J Physiol Lung Cell Mol Physiol. 2016. PMID: 27343196 Free PMC article.
82 results