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Cytokine storm in individuals with severe COVID-19 decreases endothelial cell antioxidant defense via downregulation of the Nrf2 transcriptional factor.
Rodrigues D, Machado MR, Alves JV, Fraga-Silva TFC, Martins RB, Campos LCB, Francisco DF, Couto AES, Bonato VLD, Arruda E, Becari C, Auxiliadora-Martins M, Louzada-Júnior P, Costa RM, Tostes RC. Rodrigues D, et al. Among authors: tostes rc. Am J Physiol Heart Circ Physiol. 2023 Aug 1;325(2):H252-H263. doi: 10.1152/ajpheart.00096.2023. Epub 2023 Jun 16. Am J Physiol Heart Circ Physiol. 2023. PMID: 37327001 Free PMC article.
Carotid dysfunction in senescent female mice is mediated by increased α1A-adrenoceptor activity and COX-derived vasoconstrictor prostanoids.
Costa TJ, Barros PR, Duarte DA, Silva-Neto JA, Hott SC, Santos-Silva T, Costa-Neto CM, Gomes FV, Akamine EH, McCarthy CG, Jimenez-Altayó F, Dantas AP, Tostes RC. Costa TJ, et al. Among authors: tostes rc. Am J Physiol Heart Circ Physiol. 2023 Apr 1;324(4):H417-H429. doi: 10.1152/ajpheart.00495.2022. Epub 2023 Jan 27. Am J Physiol Heart Circ Physiol. 2023. PMID: 36705993 Free article.
Inhibition of IL-6 signaling prevents serum-induced umbilical cord artery dysfunction from patients with severe COVID-19.
Almeida CR, Lima JF, Machado MR, Alves JV, Couto AES, Campos LCB, Avila-Mesquita CD, Auxiliadora-Martins M, Becari C, Louzada-Júnior P, Tostes RC, Lobato NS, Costa RM. Almeida CR, et al. Among authors: tostes rc. Am J Physiol Regul Integr Comp Physiol. 2023 Apr 1;324(4):R435-R445. doi: 10.1152/ajpregu.00154.2022. Epub 2023 Feb 3. Am J Physiol Regul Integr Comp Physiol. 2023. PMID: 36737252 Free PMC article.
The effects of female sexual hormones on the endothelial glycocalyx.
Potje SR, Martins NS, Benatti MN, Rodrigues D, Bonato VLD, Tostes RC. Potje SR, et al. Among authors: tostes rc. Curr Top Membr. 2023;91:89-137. doi: 10.1016/bs.ctm.2023.02.005. Epub 2023 Mar 10. Curr Top Membr. 2023. PMID: 37080682 Review.
Type I collagen proteolysis by matrix metalloproteinase-2 contributes to focal adhesion kinase activation and vascular smooth muscle cell proliferation in the aorta in early hypertension.
de Oliveira Neves VG, Blascke de Mello MM, Rodrigues D, Pernomian L, de Oliveira IS, Parente JM, Arantes EC, Tostes RC, Castro MM. de Oliveira Neves VG, et al. Among authors: tostes rc. Vascul Pharmacol. 2023 Oct;152:107211. doi: 10.1016/j.vph.2023.107211. Epub 2023 Aug 20. Vascul Pharmacol. 2023. PMID: 37607602
Airway epithelial cells and macrophages trigger IL-6-CD95/CD95L axis and mediate initial immunopathology of COVID-19.
Fraga-Silva TFC, Cipriano UG, Fumagalli MJ, Correa GF, Fuzo CA, Dos-Santos D, Mestriner FLAC, Becari C, Teixeira-Carvalho A, Coelho-Dos-Reis J, Menegueti MG, Figueiredo LTM, Cunha LD, Martins-Filho OA, Dias-Baruffi M, Auxiliadora-Martins M, Tostes RC, Bonato VLD. Fraga-Silva TFC, et al. Among authors: tostes rc. iScience. 2023 Oct 31;26(12):108366. doi: 10.1016/j.isci.2023.108366. eCollection 2023 Dec 15. iScience. 2023. PMID: 38047070 Free PMC article.
Alpha 1-acid glycoprotein is upregulated in severe COVID-19 patients and decreases neutrophil NETs in SARS-CoV-2 infection.
Mestriner F, Francisco DF, Campos LCB, Couto AES, Fraga-Silva TFC, Flora Dugaich V, D Avila-Mesquita C, Zukowski Kovacs H, Vasconcelos JL, Milani ER, Santos Guedes de Sá K, Martins R, Jordani MC, Corsi CAC, Barbosa JM, Vasconcelos T, Gonçalves Menegueti M, Neto J, da Costa RM, Evora PRB, Arruda E, Tostes R, Polonis K, Bonato VLD, Auxiliadora-Martins M, Ribeiro MS, Becari C. Mestriner F, et al. Cytokine. 2024 Apr;176:156503. doi: 10.1016/j.cyto.2024.156503. Epub 2024 Jan 31. Cytokine. 2024. PMID: 38301358
263 results