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Contribution analysis of metabolic tissues on systemic exposure of an active metabolite after oral administration of verapamil using a stable isotope-labeled compound.
Kataoka M, Ohshiro S, Minami K, Hasegawa T, Higashino H, Takagi T, Togashi K, Mutaguchi K, Yamashita S. Kataoka M, et al. Among authors: takagi t. Drug Metab Pharmacokinet. 2023 Aug;51:100514. doi: 10.1016/j.dmpk.2023.100514. Epub 2023 May 19. Drug Metab Pharmacokinet. 2023. PMID: 37364522
Importance of Gastric Secretion and the Rapid Gastric Emptying of Ingested Water along the Lesser Curvature ("Magenstraße") in Predicting the In Vivo Performance of Liquid Oral Dosage Forms in the Fed State Using a Modeling and Simulation.
Kiyota T, Kambayashi A, Takagi T, Yamashita S. Kiyota T, et al. Among authors: takagi t. Mol Pharm. 2022 Feb 7;19(2):642-653. doi: 10.1021/acs.molpharmaceut.1c00778. Epub 2022 Jan 25. Mol Pharm. 2022. PMID: 35075899
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