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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 3
2003 2
2004 3
2005 9
2006 2
2007 1
2008 1
2009 3
2010 5
2011 3
2012 2
2013 4
2014 3
2015 1
2017 1
2018 1
2020 2
2021 2
2022 2
2023 2
2024 0

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48 results

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Page 1
Discovery of a Tricyclic β-Lactam as a Potent Antimicrobial Agent against Carbapenem-Resistant Enterobacterales, Including Strains with Reduced Membrane Permeability and Four-Amino Acid Insertion into Penicillin-Binding Protein 3: Structure-Activity-Relationships and In Vitro and In Vivo Activities.
Sato J, Kusano H, Aoki T, Shibuya S, Yokoo K, Komano K, Oguma T, Matsumoto S, Nakamura R, Sato T, Yamawaki K. Sato J, et al. Among authors: aoki t. ACS Infect Dis. 2022 Mar 11;8(3):400-410. doi: 10.1021/acsinfecdis.1c00549. Epub 2022 Feb 3. ACS Infect Dis. 2022. PMID: 35112852
Discovery of 2-Sulfinyl-Diazabicyclooctane Derivatives, Potential Oral β-Lactamase Inhibitors for Infections Caused by Serine β-Lactamase-Producing Enterobacterales.
Fujiu M, Yokoo K, Sato J, Shibuya S, Komano K, Kusano H, Sato S, Aoki T, Kohira N, Kanazawa S, Watari R, Kawachi T, Hirakawa Y, Nagamatsu D, Kashiwagi E, Maki H, Yamawaki K. Fujiu M, et al. Among authors: aoki t. J Med Chem. 2021 Jul 8;64(13):9496-9512. doi: 10.1021/acs.jmedchem.1c00799. Epub 2021 Jun 18. J Med Chem. 2021. PMID: 34143627
Introduction of a Thio Functional Group to Diazabicyclooctane: An Effective Modification to Potentiate the Activity of β-Lactams against Gram-Negative Bacteria Producing Class A, C, and D Serine β-Lactamases.
Fujiu M, Yokoo K, Sato J, Shibuya S, Komano K, Kusano H, Sato S, Aoki T, Kohira N, Miyagawa S, Kawachi T, Yamawaki K. Fujiu M, et al. Among authors: aoki t. ACS Infect Dis. 2020 Nov 13;6(11):3034-3047. doi: 10.1021/acsinfecdis.0c00560. Epub 2020 Nov 4. ACS Infect Dis. 2020. PMID: 33147950
Cefiderocol (S-649266), A new siderophore cephalosporin exhibiting potent activities against Pseudomonas aeruginosa and other gram-negative pathogens including multi-drug resistant bacteria: Structure activity relationship.
Aoki T, Yoshizawa H, Yamawaki K, Yokoo K, Sato J, Hisakawa S, Hasegawa Y, Kusano H, Sano M, Sugimoto H, Nishitani Y, Sato T, Tsuji M, Nakamura R, Nishikawa T, Yamano Y. Aoki T, et al. Eur J Med Chem. 2018 Jul 15;155:847-868. doi: 10.1016/j.ejmech.2018.06.014. Epub 2018 Jun 8. Eur J Med Chem. 2018. PMID: 29960205
48 results