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Biological properties of IDN5174, a new synthetic camptothecin with the open lactone ring.
Beretta GL, Petrangolini G, De Cesare M, Pratesi G, Perego P, Tinelli S, Tortoreto M, Zucchetti M, Frapolli R, Bello E, Manzotti C, Fontana G, Bombardelli E, Battaglia A, Samorì C, Zunino F. Beretta GL, et al. Among authors: tortoreto m. Cancer Res. 2006 Nov 15;66(22):10976-82. doi: 10.1158/0008-5472.CAN-06-2158. Cancer Res. 2006. PMID: 17108136
Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment.
Bertolini G, Roz L, Perego P, Tortoreto M, Fontanella E, Gatti L, Pratesi G, Fabbri A, Andriani F, Tinelli S, Roz E, Caserini R, Lo Vullo S, Camerini T, Mariani L, Delia D, Calabrò E, Pastorino U, Sozzi G. Bertolini G, et al. Among authors: tortoreto m. Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16281-6. doi: 10.1073/pnas.0905653106. Epub 2009 Sep 10. Proc Natl Acad Sci U S A. 2009. PMID: 19805294 Free PMC article.
The curative efficacy of namitecan (ST1968) in preclinical models of pediatric sarcoma is associated with antiangiogenic effects.
Cassinelli G, Zuco V, Petrangolini G, De Cesare M, Tortoreto M, Lanzi C, Cominetti D, Zaffaroni N, Orlandi A, Passeri D, Meco D, Di Francesco AM, Riccardi R, Bucci F, Pisano C, Zunino F. Cassinelli G, et al. Among authors: tortoreto m. Biochem Pharmacol. 2012 Jul 15;84(2):163-71. doi: 10.1016/j.bcp.2012.04.005. Epub 2012 Apr 13. Biochem Pharmacol. 2012. PMID: 22525722
Anti-tumor activity of CpG-ODN aerosol in mouse lung metastases.
Sfondrini L, Sommariva M, Tortoreto M, Meini A, Piconese S, Calvaruso M, Van Rooijen N, Bonecchi R, Zaffaroni N, Colombo MP, Tagliabue E, Balsari A. Sfondrini L, et al. Among authors: tortoreto m. Int J Cancer. 2013 Jul 15;133(2):383-93. doi: 10.1002/ijc.28028. Epub 2013 Feb 12. Int J Cancer. 2013. PMID: 23319306 Free article.
Antitumor efficacy of the heparanase inhibitor SST0001 alone and in combination with antiangiogenic agents in the treatment of human pediatric sarcoma models.
Cassinelli G, Lanzi C, Tortoreto M, Cominetti D, Petrangolini G, Favini E, Zaffaroni N, Pisano C, Penco S, Vlodavsky I, Zunino F. Cassinelli G, et al. Among authors: tortoreto m. Biochem Pharmacol. 2013 May 15;85(10):1424-32. doi: 10.1016/j.bcp.2013.02.023. Epub 2013 Mar 1. Biochem Pharmacol. 2013. PMID: 23466421
Synergistic cooperation between sunitinib and cisplatin promotes apoptotic cell death in human medullary thyroid cancer.
Lopergolo A, Nicolini V, Favini E, Dal Bo L, Tortoreto M, Cominetti D, Folini M, Perego P, Castiglioni V, Scanziani E, Borrello MG, Zaffaroni N, Cassinelli G, Lanzi C. Lopergolo A, et al. Among authors: tortoreto m. J Clin Endocrinol Metab. 2014 Feb;99(2):498-509. doi: 10.1210/jc.2013-2574. Epub 2013 Nov 25. J Clin Endocrinol Metab. 2014. PMID: 24276455
Pleiotropic antitumor effects of the pan-HDAC inhibitor ITF2357 against c-Myc-overexpressing human B-cell non-Hodgkin lymphomas.
Zappasodi R, Cavanè A, Iorio MV, Tortoreto M, Guarnotta C, Ruggiero G, Piovan C, Magni M, Zaffaroni N, Tagliabue E, Croce CM, Zunino F, Gianni AM, Di Nicola M. Zappasodi R, et al. Among authors: tortoreto m. Int J Cancer. 2014 Nov 1;135(9):2034-45. doi: 10.1002/ijc.28852. Epub 2014 Mar 26. Int J Cancer. 2014. PMID: 24648290 Free article.
80 results