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Repurposing doxycycline for synucleinopathies: remodelling of α-synuclein oligomers towards non-toxic parallel beta-sheet structured species.
González-Lizárraga F, Socías SB, Ávila CL, Torres-Bugeau CM, Barbosa LR, Binolfi A, Sepúlveda-Díaz JE, Del-Bel E, Fernandez CO, Papy-Garcia D, Itri R, Raisman-Vozari R, Chehín RN. González-Lizárraga F, et al. Among authors: torres bugeau cm. Sci Rep. 2017 Feb 3;7:41755. doi: 10.1038/srep41755. Sci Rep. 2017. PMID: 28155912 Free PMC article.
Structural characterization of heparin-induced glyceraldehyde-3-phosphate dehydrogenase protofibrils preventing α-synuclein oligomeric species toxicity.
Ávila CL, Torres-Bugeau CM, Barbosa LR, Sales EM, Ouidja MO, Socías SB, Celej MS, Raisman-Vozari R, Papy-Garcia D, Itri R, Chehín RN. Ávila CL, et al. Among authors: torres bugeau cm. J Biol Chem. 2014 May 16;289(20):13838-50. doi: 10.1074/jbc.M113.544288. Epub 2014 Mar 26. J Biol Chem. 2014. PMID: 24671416 Free PMC article.