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Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration.
Felszeghy S, Viiri J, Paterno JJ, Hyttinen JMT, Koskela A, Chen M, Leinonen H, Tanila H, Kivinen N, Koistinen A, Toropainen E, Amadio M, Smedowski A, Reinisalo M, Winiarczyk M, Mackiewicz J, Mutikainen M, Ruotsalainen AK, Kettunen M, Jokivarsi K, Sinha D, Kinnunen K, Petrovski G, Blasiak J, Bjørkøy G, Koskelainen A, Skottman H, Urtti A, Salminen A, Kannan R, Ferrington DA, Xu H, Levonen AL, Tavi P, Kauppinen A, Kaarniranta K. Felszeghy S, et al. Among authors: toropainen e. Redox Biol. 2019 Jan;20:1-12. doi: 10.1016/j.redox.2018.09.011. Epub 2018 Sep 14. Redox Biol. 2019. PMID: 30253279 Free PMC article.
Cell culture models of the ocular barriers.
Hornof M, Toropainen E, Urtti A. Hornof M, et al. Among authors: toropainen e. Eur J Pharm Biopharm. 2005 Jul;60(2):207-25. doi: 10.1016/j.ejpb.2005.01.009. Eur J Pharm Biopharm. 2005. PMID: 15939234 Review.
Mechanisms of protein aggregation in the retinal pigment epithelial cells.
Kaarniranta K, Hyttinen J, Ryhanen T, Viiri J, Paimela T, Toropainen E, Sorri I, Salminen A. Kaarniranta K, et al. Among authors: toropainen e. Front Biosci (Elite Ed). 2010 Jun 1;2(4):1374-84. doi: 10.2741/e198. Front Biosci (Elite Ed). 2010. PMID: 20515810 Free article. Review.
A critical assessment of in vitro tissue models for ADME and drug delivery.
Vellonen KS, Malinen M, Mannermaa E, Subrizi A, Toropainen E, Lou YR, Kidron H, Yliperttula M, Urtti A. Vellonen KS, et al. Among authors: toropainen e. J Control Release. 2014 Sep 28;190:94-114. doi: 10.1016/j.jconrel.2014.06.044. Epub 2014 Jun 30. J Control Release. 2014. PMID: 24993429 Review.
53 results