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Design, synthesis, kinetic, molecular dynamics, and hypoglycemic effect characterization of new and potential selective benzimidazole derivatives as Protein Tyrosine Phosphatase 1B inhibitors.
Campos-Almazán MI, Flores-Ramos M, Hernández-Campos A, Castillo R, Sierra-Campos E, Torgeson K, Peti W, Valdez-Solana M, Oria-Hernández J, Méndez ST, Castillo-Villanueva A, Jiménez-de Jesús H, Avitia-Domínguez C, Téllez-Valencia A. Campos-Almazán MI, et al. Among authors: torgeson k. Bioorg Med Chem. 2021 Oct 15;48:116418. doi: 10.1016/j.bmc.2021.116418. Epub 2021 Sep 17. Bioorg Med Chem. 2021. PMID: 34563877
Conserved conformational dynamics determine enzyme activity.
Torgeson KR, Clarkson MW, Granata D, Lindorff-Larsen K, Page R, Peti W. Torgeson KR, et al. Sci Adv. 2022 Aug 5;8(31):eabo5546. doi: 10.1126/sciadv.abo5546. Epub 2022 Aug 3. Sci Adv. 2022. PMID: 35921420 Free PMC article.
Scalability and Sustainability of a Surgical Infection Prevention Program in Low-Income Environments.
Starr N, Gebeyehu N, Nofal MR, Forrester JA, Tesfaye A, Mammo TN, Weiser TG; and Lifebox Clean Cut Collaborative; Amdie DA, Abreha M, Alemu M, Ally S, Abdukadir AA, Assefa G, Bedore Y, Bekele A, Berhanu M, Alemu SB, Chimdesa Z, Derbew M, Fast C, Fernandez K, Kahsay S, Kassahun A, Kebede H, Kitesa G, Koritsanszky L, Lima B, Mellese B, Mengistu M, Negash S, Tara M, Taye S, Torgeson K, Tsehaye M, Tiruneh A, Stave K. Starr N, et al. Among authors: torgeson k. JAMA Surg. 2024 Feb 1;159(2):161-169. doi: 10.1001/jamasurg.2023.6033. JAMA Surg. 2024. PMID: 38019510