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Therapeutic Targeting of the Soluble Guanylate Cyclase.
Makrynitsa GI, Zompra AA, Argyriou AI, Spyroulias GA, Topouzis S. Makrynitsa GI, et al. Among authors: topouzis s. Curr Med Chem. 2019;26(15):2730-2747. doi: 10.2174/0929867326666190108095851. Curr Med Chem. 2019. PMID: 30621555 Review.
Replacement of heme by soluble guanylate cyclase (sGC) activators abolishes heme-nitric oxide/oxygen (H-NOX) domain structural plasticity.
Argyriou AI, Makrynitsa GI, Dalkas G, Georgopoulou DA, Salagiannis K, Vazoura V, Papapetropoulos A, Topouzis S, Spyroulias GA. Argyriou AI, et al. Among authors: topouzis s. Curr Res Struct Biol. 2021 Nov 18;3:324-336. doi: 10.1016/j.crstbi.2021.11.003. eCollection 2021. Curr Res Struct Biol. 2021. PMID: 34901882 Free PMC article.
Thioglycine and L-thiovaline: biologically active H₂S-donors.
Zhou Z, von Wantoch Rekowski M, Coletta C, Szabo C, Bucci M, Cirino G, Topouzis S, Papapetropoulos A, Giannis A. Zhou Z, et al. Among authors: topouzis s. Bioorg Med Chem. 2012 Apr 15;20(8):2675-8. doi: 10.1016/j.bmc.2012.02.028. Epub 2012 Feb 27. Bioorg Med Chem. 2012. PMID: 22436388
Role of cGMP in hydrogen sulfide signaling.
Bibli SI, Yang G, Zhou Z, Wang R, Topouzis S, Papapetropoulos A. Bibli SI, et al. Among authors: topouzis s. Nitric Oxide. 2015 Apr 30;46:7-13. doi: 10.1016/j.niox.2014.12.004. Epub 2014 Dec 29. Nitric Oxide. 2015. PMID: 25553675 Review.
Nurr1:RXRα heterodimer activation as monotherapy for Parkinson's disease.
Spathis AD, Asvos X, Ziavra D, Karampelas T, Topouzis S, Cournia Z, Qing X, Alexakos P, Smits LM, Dalla C, Rideout HJ, Schwamborn JC, Tamvakopoulos C, Fokas D, Vassilatis DK. Spathis AD, et al. Among authors: topouzis s. Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):3999-4004. doi: 10.1073/pnas.1616874114. Epub 2017 Mar 27. Proc Natl Acad Sci U S A. 2017. PMID: 28348207 Free PMC article.
Comparison of the effects of e-cigarette vapor with cigarette smoke on lung function and inflammation in mice.
Glynos C, Bibli SI, Katsaounou P, Pavlidou A, Magkou C, Karavana V, Topouzis S, Kalomenidis I, Zakynthinos S, Papapetropoulos A. Glynos C, et al. Among authors: topouzis s. Am J Physiol Lung Cell Mol Physiol. 2018 Nov 1;315(5):L662-L672. doi: 10.1152/ajplung.00389.2017. Epub 2018 Aug 9. Am J Physiol Lung Cell Mol Physiol. 2018. PMID: 30091379 Free article.
Guanylyl cyclase activation reverses resistive breathing-induced lung injury and inflammation.
Glynos C, Toumpanakis D, Loverdos K, Karavana V, Zhou Z, Magkou C, Dettoraki M, Perlikos F, Pavlidou A, Kotsikoris V, Topouzis S, Theocharis SE, Brouckaert P, Giannis A, Papapetropoulos A, Vassilakopoulos T. Glynos C, et al. Among authors: topouzis s. Am J Respir Cell Mol Biol. 2015 Jun;52(6):762-71. doi: 10.1165/rcmb.2014-0092OC. Am J Respir Cell Mol Biol. 2015. PMID: 25353067 Free article.
38 results