Toplak A - Search Results

1

Natural Occurring and Engineered Enzymes for Peptide Ligation and Cyclization.

Nuijens T, Toplak A, Schmidt M, Ricci A, Cabri W. Nuijens T, et al. Among authors: toplak a. Front Chem. 2019 Nov 29;7:829. doi: 10.3389/fchem.2019.00829. eCollection 2019. Front Chem. 2019. PMID: 31850317 Free PMC article. Review.

2

Enzyme-mediated ligation technologies for peptides and proteins.

Schmidt M, Toplak A, Quaedflieg PJ, Nuijens T. Schmidt M, et al. Among authors: toplak a. Curr Opin Chem Biol. 2017 Jun;38:1-7. doi: 10.1016/j.cbpa.2017.01.017. Epub 2017 Apr 20. Curr Opin Chem Biol. 2017. PMID: 28229906 Review.

3

Enzyme-catalyzed peptide cyclization.

Schmidt M, Toplak A, Quaedflieg PJLM, van Maarseveen JH, Nuijens T. Schmidt M, et al. Among authors: toplak a. Drug Discov Today Technol. 2017 Dec;26:11-16. doi: 10.1016/j.ddtec.2017.11.007. Epub 2017 Nov 26. Drug Discov Today Technol. 2017. PMID: 29249237 Review.

4

Design of a substrate-tailored peptiligase variant for the efficient synthesis of thymosin-α₁.

Schmidt M, Toplak A, Rozeboom HJ, Wijma HJ, Quaedflieg PJLM, van Maarseveen JH, Janssen DB, Nuijens T. Schmidt M, et al. Among authors: toplak a. Org Biomol Chem. 2018 Jan 24;16(4):609-618. doi: 10.1039/c7ob02812a. Org Biomol Chem. 2018. PMID: 29300408

5

Efficient Enzymatic Cyclization of Disulfide-Rich Peptides by Using Peptide Ligases.

Schmidt M, Huang YH, Texeira de Oliveira EF, Toplak A, Wijma HJ, Janssen DB, van Maarseveen JH, Craik DJ, Nuijens T. Schmidt M, et al. Among authors: toplak a. Chembiochem. 2019 Jun 14;20(12):1524-1529. doi: 10.1002/cbic.201900033. Epub 2019 Apr 25. Chembiochem. 2019. PMID: 30735312

6

From thiol-subtilisin to omniligase: Design and structure of a broadly applicable peptide ligase.

Toplak A, Teixeira de Oliveira EF, Schmidt M, Rozeboom HJ, Wijma HJ, Meekels LKM, de Visser R, Janssen DB, Nuijens T. Toplak A, et al. Comput Struct Biotechnol J. 2021 Feb 9;19:1277-1287. doi: 10.1016/j.csbj.2021.02.002. eCollection 2021. Comput Struct Biotechnol J. 2021. PMID: 33717424 Free PMC article.

7

Peptide synthesis in neat organic solvents with novel thermostable proteases.

Toplak A, Nuijens T, Quaedflieg PJ, Wu B, Janssen DB. Toplak A, et al. Enzyme Microb Technol. 2015 Jun;73-74:20-8. doi: 10.1016/j.enzmictec.2015.03.003. Epub 2015 Mar 11. Enzyme Microb Technol. 2015. PMID: 26002500

8

Proteolysin, a novel highly thermostable and cosolvent-compatible protease from the thermophilic bacterium Coprothermobacter proteolyticus.

Toplak A, Wu B, Fusetti F, Quaedflieg PJ, Janssen DB. Toplak A, et al. Appl Environ Microbiol. 2013 Sep;79(18):5625-32. doi: 10.1128/AEM.01479-13. Epub 2013 Jul 12. Appl Environ Microbiol. 2013. PMID: 23851086 Free PMC article.

9

Design, synthesis, and in vitro activity of novel 2'-O-substituted 15-membered azalides.

Pešić D, Starčević K, Toplak A, Herreros E, Vidal J, Almela MJ, Jelić D, Alihodžić S, Spaventi R, Perić M. Pešić D, et al. Among authors: toplak a. J Med Chem. 2012 Apr 12;55(7):3216-27. doi: 10.1021/jm201676t. Epub 2012 Mar 23. J Med Chem. 2012. PMID: 22380766

10

Surgery for Degenerative Cervical Myelopathy: What Really Counts?

Gembruch O, Jabbarli R, Rashidi A, Chihi M, Hetze S, Barthel L, Toplak A, El Hindy N, Sure U, Dammann P, Özkan N. Gembruch O, et al. Among authors: toplak a. Spine (Phila Pa 1976). 2021 Mar 1;46(5):294-299. doi: 10.1097/BRS.0000000000003750. Spine (Phila Pa 1976). 2021. PMID: 33065693

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