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Regulation of p53 localization and activity by Ubc13.
Laine A, Topisirovic I, Zhai D, Reed JC, Borden KL, Ronai Z. Laine A, et al. Among authors: topisirovic i. Mol Cell Biol. 2006 Dec;26(23):8901-13. doi: 10.1128/MCB.01156-06. Epub 2006 Sep 25. Mol Cell Biol. 2006. PMID: 17000756 Free PMC article.
Control of p53 multimerization by Ubc13 is JNK-regulated.
Topisirovic I, Gutierrez GJ, Chen M, Appella E, Borden KL, Ronai ZA. Topisirovic I, et al. Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):12676-81. doi: 10.1073/pnas.0900596106. Epub 2009 Jul 27. Proc Natl Acad Sci U S A. 2009. PMID: 19651615 Free PMC article.
Degradation of newly synthesized polypeptides by ribosome-associated RACK1/c-Jun N-terminal kinase/eukaryotic elongation factor 1A2 complex.
Gandin V, Gutierrez GJ, Brill LM, Varsano T, Feng Y, Aza-Blanc P, Au Q, McLaughlan S, Ferreira TA, Alain T, Sonenberg N, Topisirovic I, Ronai ZA. Gandin V, et al. Among authors: topisirovic i. Mol Cell Biol. 2013 Jul;33(13):2510-26. doi: 10.1128/MCB.01362-12. Epub 2013 Apr 22. Mol Cell Biol. 2013. PMID: 23608534 Free PMC article.
RACK1 Function in Cell Motility and Protein Synthesis.
Gandin V, Senft D, Topisirovic I, Ronai ZA. Gandin V, et al. Among authors: topisirovic i. Genes Cancer. 2013 Sep;4(9-10):369-77. doi: 10.1177/1947601913486348. Genes Cancer. 2013. PMID: 24349634 Free PMC article. Review.
SBI-0640756 Attenuates the Growth of Clinically Unresponsive Melanomas by Disrupting the eIF4F Translation Initiation Complex.
Feng Y, Pinkerton AB, Hulea L, Zhang T, Davies MA, Grotegut S, Cheli Y, Yin H, Lau E, Kim H, De SK, Barile E, Pellecchia M, Bosenberg M, Li JL, James B, Hassig CA, Brown KM, Topisirovic I, Ronai ZA. Feng Y, et al. Among authors: topisirovic i. Cancer Res. 2015 Dec 15;75(24):5211-8. doi: 10.1158/0008-5472.CAN-15-0885. Epub 2015 Nov 24. Cancer Res. 2015. PMID: 26603897 Free PMC article.
Translational reprogramming marks adaptation to asparagine restriction in cancer.
Pathria G, Lee JS, Hasnis E, Tandoc K, Scott DA, Verma S, Feng Y, Larue L, Sahu AD, Topisirovic I, Ruppin E, Ronai ZA. Pathria G, et al. Among authors: topisirovic i. Nat Cell Biol. 2019 Dec;21(12):1590-1603. doi: 10.1038/s41556-019-0415-1. Epub 2019 Nov 18. Nat Cell Biol. 2019. PMID: 31740775 Free PMC article.
SPANX Control of Lamin A/C Modulates Nuclear Architecture and Promotes Melanoma Growth.
Lazar I, Fabre B, Feng Y, Khateb A, Turko P, Martinez Gomez JM, Frederick DT, Levesque MP, Feld L, Zhang G, Zhang T, James B, Shklover J, Avitan-Hersh E, Livneh I, Scortegagna M, Brown K, Larsson O, Topisirovic I, Wolfenson H, Herlyn M, Flaherty K, Dummer R, Ronai ZA. Lazar I, et al. Among authors: topisirovic i. Mol Cancer Res. 2020 Oct;18(10):1560-1573. doi: 10.1158/1541-7786.MCR-20-0291. Epub 2020 Jun 22. Mol Cancer Res. 2020. PMID: 32571981 Free PMC article.
Inhibition of coronavirus HCoV-OC43 by targeting the eIF4F complex.
Feng Y, Grotegut S, Jovanovic P, Gandin V, Olson SH, Murad R, Beall A, Colayco S, De-Jesus P, Chanda S, English BP, Singer RH, Jackson M, Topisirovic I, Ronai ZA. Feng Y, et al. Among authors: topisirovic i. Front Pharmacol. 2022 Dec 1;13:1029093. doi: 10.3389/fphar.2022.1029093. eCollection 2022. Front Pharmacol. 2022. PMID: 36532738 Free PMC article.
132 results