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Complement lectin pathway activation is associated with COVID-19 disease severity, independent of MBL2 genotype subgroups.
Hurler L, Szilágyi Á, Mescia F, Bergamaschi L, Mező B, Sinkovits G, Réti M, Müller V, Iványi Z, Gál J, Gopcsa L, Reményi P, Szathmáry B, Lakatos B, Szlávik J, Bobek I, Prohászka ZZ, Förhécz Z, Csuka D, Kajdácsi E, Cervenak L, Kiszel P, Masszi T, Vályi-Nagy I, Würzner R; Cambridge Institute of Therapeutic Immunology and Infectious Disease-National Institute of Health Research (CITIID-NIHR) COVID BioResource Collaboration; Lyons PA, Toonen EJM, Prohászka Z. Hurler L, et al. Among authors: toonen ejm. Front Immunol. 2023 Mar 27;14:1162171. doi: 10.3389/fimmu.2023.1162171. eCollection 2023. Front Immunol. 2023. PMID: 37051252 Free PMC article.
Evidence, detailed characterization and clinical context of complement activation in acute multisystem inflammatory syndrome in children.
Sinkovits G, Schnur J, Hurler L, Kiszel P, Prohászka ZZ, Sík P, Kajdácsi E, Cervenak L, Maráczi V, Dávid M, Zsigmond B, Rimanóczy É, Bereczki C, Willems L, Toonen EJM, Prohászka Z. Sinkovits G, et al. Among authors: toonen ejm. Sci Rep. 2022 Nov 17;12(1):19759. doi: 10.1038/s41598-022-23806-5. Sci Rep. 2022. PMID: 36396679 Free PMC article.
Distinction of early complement classical and lectin pathway activation via quantification of C1s/C1-INH and MASP-1/C1-INH complexes using novel ELISAs.
Hurler L, Toonen EJM, Kajdácsi E, van Bree B, Brandwijk RJMGE, de Bruin W, Lyons PA, Bergamaschi L; Cambridge Institute of Therapeutic Immunology and Infectious Disease-National Institute of Health Research (CITIID-NIHR) COVID BioResource Collaboration; Sinkovits G, Cervenak L, Würzner R, Prohászka Z. Hurler L, et al. Among authors: toonen ejm. Front Immunol. 2022 Nov 4;13:1039765. doi: 10.3389/fimmu.2022.1039765. eCollection 2022. Front Immunol. 2022. PMID: 36420270 Free PMC article.
Editorial: Current challenges in complement diagnostics.
Nilsson PH, Skattum L, Toonen EJM. Nilsson PH, et al. Among authors: toonen ejm. Front Immunol. 2023 Nov 24;14:1334050. doi: 10.3389/fimmu.2023.1334050. eCollection 2023. Front Immunol. 2023. PMID: 38077347 Free PMC article. No abstract available.
Complement C7 and clusterin form a complex in circulation.
Massri M, Toonen EJM, Sarg B, Kremser L, Grasse M, Fleischer V, Torres-Quesada O, Hengst L, Skjoedt MO, Bayarri-Olmos R, Rosbjerg A, Garred P, Orth-Höller D, Prohászka Z, Würzner R. Massri M, et al. Among authors: toonen ejm. Front Immunol. 2024 Jan 25;15:1330095. doi: 10.3389/fimmu.2024.1330095. eCollection 2024. Front Immunol. 2024. PMID: 38333209 Free PMC article.
Transient anti-cytokine autoantibodies superimpose the hyperinflammatory response in Kawasaki disease and multisystem inflammatory syndrome in children: a comparative cohort study on correlates of disease.
Netea SA, Biesbroek G, van Stijn D, Ijspeert H, van der Made CI, Jansen MH, Geissler J, van den Berg JMM, van der Kuip M, Gruppen MP, Schonenberg-Meinema D, Kapitein B, van Furth AMMT, Nagelkerke SQ, Pajkrt D, Plötz FB, den Boer MEJL, Landman GW, van Houten MA, Goetschalckx I; Kawasaki Study Group; Toonen EJM, van de Veerdonk FL, Kuipers IM, Dik WA, Kuijpers TW. Netea SA, et al. Among authors: toonen ejm. EBioMedicine. 2023 Sep;95:104736. doi: 10.1016/j.ebiom.2023.104736. Epub 2023 Jul 29. EBioMedicine. 2023. PMID: 37524002 Free PMC article.
45 results