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Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer's disease.
De Schepper S, Ge JZ, Crowley G, Ferreira LSS, Garceau D, Toomey CE, Sokolova D, Rueda-Carrasco J, Shin SH, Kim JS, Childs T, Lashley T, Burden JJ, Sasner M, Sala Frigerio C, Jung S, Hong S. De Schepper S, et al. Among authors: toomey ce. Nat Neurosci. 2023 Mar;26(3):406-415. doi: 10.1038/s41593-023-01257-z. Epub 2023 Feb 6. Nat Neurosci. 2023. PMID: 36747024 Free PMC article.
Molecular forms of neurogranin in cerebrospinal fluid.
Nazir FH, Camporesi E, Brinkmalm G, Lashley T, Toomey CE, Kvartsberg H, Zetterberg H, Blennow K, Becker B. Nazir FH, et al. Among authors: toomey ce. J Neurochem. 2021 May;157(3):816-833. doi: 10.1111/jnc.15252. Epub 2020 Dec 17. J Neurochem. 2021. PMID: 33249594 Free PMC article.
Amyloid pathology and synaptic loss in pathological aging.
Gkanatsiou E, Nilsson J, Toomey CE, Vrillon A, Kvartsberg H, Portelius E, Zetterberg H, Blennow K, Brinkmalm A, Lashley T, Brinkmalm G. Gkanatsiou E, et al. Among authors: toomey ce. J Neurochem. 2021 Oct;159(2):258-272. doi: 10.1111/jnc.15487. Epub 2021 Sep 2. J Neurochem. 2021. PMID: 34473357 Free article.
P-tau235: a novel biomarker for staging preclinical Alzheimer's disease.
Lantero-Rodriguez J, Snellman A, Benedet AL, Milà-Alomà M, Camporesi E, Montoliu-Gaya L, Ashton NJ, Vrillon A, Karikari TK, Gispert JD, Salvadó G, Shekari M, Toomey CE, Lashley TL, Zetterberg H, Suárez-Calvet M, Brinkmalm G, Rosa Neto P, Blennow K. Lantero-Rodriguez J, et al. Among authors: toomey ce. EMBO Mol Med. 2021 Dec 7;13(12):e15098. doi: 10.15252/emmm.202115098. Epub 2021 Nov 2. EMBO Mol Med. 2021. PMID: 34725927 Free PMC article.
Mitochondrial dysfunction is a key pathological driver of early stage Parkinson's.
Toomey CE, Heywood WE, Evans JR, Lachica J, Pressey SN, Foti SC, Al Shahrani M, D'Sa K, Hargreaves IP, Heales S, Orford M, Troakes C, Attems J, Gelpi E, Palkovits M, Lashley T, Gentleman SM, Revesz T, Mills K, Gandhi S. Toomey CE, et al. Acta Neuropathol Commun. 2022 Sep 8;10(1):134. doi: 10.1186/s40478-022-01424-6. Acta Neuropathol Commun. 2022. PMID: 36076304 Free PMC article.
Brain DNA methylomic analysis of frontotemporal lobar degeneration reveals OTUD4 in shared dysregulated signatures across pathological subtypes.
Fodder K, Murthy M, Rizzu P, Toomey CE, Hasan R, Humphrey J, Raj T, Lunnon K, Mill J, Heutink P, Lashley T, Bettencourt C. Fodder K, et al. Among authors: toomey ce. Acta Neuropathol. 2023 Jul;146(1):77-95. doi: 10.1007/s00401-023-02583-z. Epub 2023 May 7. Acta Neuropathol. 2023. PMID: 37149835 Free PMC article.
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