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Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer's disease.
Colom-Cadena M, Toombs J, Simzer E, Holt K, McGeachan R, Tulloch J, Jackson RJ, Catterson JH, Spires-Jones MP, Rose J, Waybright L, Caggiano AO, King D, Gobbo F, Davies C, Hooley M, Dunnett S, Tempelaar R, Meftah S, Tzioras M, Hamby ME, Izzo NJ, Catalano SM, Durrant CS, Smith C, Dando O, Spires-Jones TL. Colom-Cadena M, et al. Among authors: toombs j. Acta Neuropathol. 2024 Feb 6;147(1):32. doi: 10.1007/s00401-023-02679-6. Acta Neuropathol. 2024. PMID: 38319380 Free PMC article.
Synaptic resilience is associated with maintained cognition during ageing.
King D, Holt K, Toombs J, He X, Dando O, Okely JA, Tzioras M, Rose J, Gunn C, Correia A, Montero C, McAlister H, Tulloch J, Lamont D, Taylor AM, Harris SE, Redmond P, Cox SR, Henstridge CM, Deary IJ, Smith C, Spires-Jones TL. King D, et al. Among authors: toombs j. Alzheimers Dement. 2023 Jun;19(6):2560-2574. doi: 10.1002/alz.12894. Epub 2022 Dec 22. Alzheimers Dement. 2023. PMID: 36547260
The PSEN1 E280G mutation leads to increased amyloid-β43 production in induced pluripotent stem cell neurons and deposition in brain tissue.
Willumsen N, Arber C, Lovejoy C, Toombs J, Alatza A, Weston PSJ, Chávez-Gutiérrez L, Hardy J, Zetterberg H, Fox NC, Ryan NS, Lashley T, Wray S. Willumsen N, et al. Among authors: toombs j. Brain Commun. 2022 Dec 7;5(1):fcac321. doi: 10.1093/braincomms/fcac321. eCollection 2023. Brain Commun. 2022. PMID: 36687397 Free PMC article.
A review of materials used in tomographic volumetric additive manufacturing.
Madrid-Wolff J, Toombs J, Rizzo R, Bernal PN, Porcincula D, Walton R, Wang B, Kotz-Helmer F, Yang Y, Kaplan D, Zhang YS, Zenobi-Wong M, McLeod RR, Rapp B, Schwartz J, Shusteff M, Talyor H, Levato R, Moser C. Madrid-Wolff J, et al. Among authors: toombs j. MRS Commun. 2023;13(5):764-785. doi: 10.1557/s43579-023-00447-x. Epub 2023 Aug 29. MRS Commun. 2023. PMID: 37901477 Free PMC article. Review.
Pleiotrophin drives a prometastatic immune niche in breast cancer.
Ganguly D, Schmidt MO, Coleman M, Ngo TC, Sorrelle N, Dominguez ATA, Murimwa GZ, Toombs JE, Lewis C, Fang YV, Valdes-Mora F, Gallego-Ortega D, Wellstein A, Brekken RA. Ganguly D, et al. Among authors: toombs je. J Exp Med. 2023 May 1;220(5):e20220610. doi: 10.1084/jem.20220610. Epub 2023 Feb 24. J Exp Med. 2023. PMID: 36828390 Free PMC article.
Reducing voltage-dependent potassium channel Kv3.4 levels ameliorates synapse loss in a mouse model of Alzheimer's disease.
Yeap J, Sathyaprakash C, Toombs J, Tulloch J, Scutariu C, Rose J, Burr K, Davies C, Colom-Cadena M, Chandran S, Large CH, Rowan MJM, Gunthorpe MJ, Spires-Jones TL. Yeap J, et al. Among authors: toombs j. Brain Neurosci Adv. 2022 Mar 24;6:23982128221086464. doi: 10.1177/23982128221086464. eCollection 2022 Jan-Dec. Brain Neurosci Adv. 2022. PMID: 35359460 Free PMC article.
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