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Year Number of Results
2013 2
2014 1
2016 1
2017 1
2018 1
2019 6
2020 3
2021 4
2022 3
2023 2
2024 1

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Page 1
β-Lactamases and β-Lactamase Inhibitors in the 21st Century.
Tooke CL, Hinchliffe P, Bragginton EC, Colenso CK, Hirvonen VHA, Takebayashi Y, Spencer J. Tooke CL, et al. J Mol Biol. 2019 Aug 23;431(18):3472-3500. doi: 10.1016/j.jmb.2019.04.002. Epub 2019 Apr 5. J Mol Biol. 2019. PMID: 30959050 Free PMC article. Review.
Effect of High-Flow Nasal Cannula Therapy vs Continuous Positive Airway Pressure Following Extubation on Liberation From Respiratory Support in Critically Ill Children: A Randomized Clinical Trial.
Ramnarayan P, Richards-Belle A, Drikite L, Saull M, Orzechowska I, Darnell R, Sadique Z, Lester J, Morris KP, Tume LN, Davis PJ, Peters MJ, Feltbower RG, Grieve R, Thomas K, Mouncey PR, Harrison DA, Rowan KM; FIRST-ABC Step-Down RCT Investigators and the Paediatric Critical Care Society Study Group. Ramnarayan P, et al. JAMA. 2022 Apr 26;327(16):1555-1565. doi: 10.1001/jama.2022.3367. JAMA. 2022. PMID: 35390113 Free PMC article. Clinical Trial.
Profiling interactions of vaborbactam with metallo-β-lactamases.
Langley GW, Cain R, Tyrrell JM, Hinchliffe P, Calvopiña K, Tooke CL, Widlake E, Dowson CG, Spencer J, Walsh TR, Schofield CJ, Brem J. Langley GW, et al. Among authors: tooke cl. Bioorg Med Chem Lett. 2019 Aug 1;29(15):1981-1984. doi: 10.1016/j.bmcl.2019.05.031. Epub 2019 May 17. Bioorg Med Chem Lett. 2019. PMID: 31171422 Free PMC article.
Faropenem reacts with serine and metallo-β-lactamases to give multiple products.
Lucic A, Hinchliffe P, Malla TR, Tooke CL, Brem J, Calvopiña K, Lohans CT, Rabe P, McDonough MA, Armistead T, Orville AM, Spencer J, Schofield CJ. Lucic A, et al. Among authors: tooke cl. Eur J Med Chem. 2021 Apr 5;215:113257. doi: 10.1016/j.ejmech.2021.113257. Epub 2021 Feb 9. Eur J Med Chem. 2021. PMID: 33618159 Free PMC article.
An on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography.
Butryn A, Simon PS, Aller P, Hinchliffe P, Massad RN, Leen G, Tooke CL, Bogacz I, Kim IS, Bhowmick A, Brewster AS, Devenish NE, Brem J, Kamps JJAG, Lang PA, Rabe P, Axford D, Beale JH, Davy B, Ebrahim A, Orlans J, Storm SLS, Zhou T, Owada S, Tanaka R, Tono K, Evans G, Owen RL, Houle FA, Sauter NK, Schofield CJ, Spencer J, Yachandra VK, Yano J, Kern JF, Orville AM. Butryn A, et al. Among authors: tooke cl. Nat Commun. 2021 Jul 22;12(1):4461. doi: 10.1038/s41467-021-24757-7. Nat Commun. 2021. PMID: 34294694 Free PMC article.
Should DEHP be eliminated in blood bags?
van der Meer PF, Reesink HW, Panzer S, Wong J, Ismay S, Keller A, Pink J, Buchta C, Compernolle V, Wendel S, Biagini S, Scuracchio P, Thibault L, Germain M, Georgsen J, Bégué S, Dernis D, Raspollini E, Villa S, Rebulla P, Takanashi M, de Korte D, Lozano M, Cid J, Gulliksson H, Cardigan R, Tooke C, Fung MK, Luban NL, Vassallo R, Benjamin R. van der Meer PF, et al. Among authors: tooke c. Vox Sang. 2014 Feb;106(2):176-95. doi: 10.1111/vox.12099. Epub 2013 Dec 12. Vox Sang. 2014. PMID: 24330039 No abstract available.
Molecular Basis of Class A β-Lactamase Inhibition by Relebactam.
Tooke CL, Hinchliffe P, Lang PA, Mulholland AJ, Brem J, Schofield CJ, Spencer J. Tooke CL, et al. Antimicrob Agents Chemother. 2019 Sep 23;63(10):e00564-19. doi: 10.1128/AAC.00564-19. Print 2019 Oct. Antimicrob Agents Chemother. 2019. PMID: 31383664 Free PMC article.
23 results