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Rescue of Hippo coactivator YAP1 triggers DNA damage-induced apoptosis in hematological cancers.
Cottini F, Hideshima T, Xu C, Sattler M, Dori M, Agnelli L, ten Hacken E, Bertilaccio MT, Antonini E, Neri A, Ponzoni M, Marcatti M, Richardson PG, Carrasco R, Kimmelman AC, Wong KK, Caligaris-Cappio F, Blandino G, Kuehl WM, Anderson KC, Tonon G. Cottini F, et al. Among authors: tonon g. Nat Med. 2014 Jun;20(6):599-606. doi: 10.1038/nm.3562. Epub 2014 May 11. Nat Med. 2014. PMID: 24813251 Free PMC article.
Che-1-induced inhibition of mTOR pathway enables stress-induced autophagy.
Desantis A, Bruno T, Catena V, De Nicola F, Goeman F, Iezzi S, Sorino C, Ponzoni M, Bossi G, Federico V, La Rosa F, Ricciardi MR, Lesma E, De Meo PD, Castrignanò T, Petrucci MT, Pisani F, Chesi M, Bergsagel PL, Floridi A, Tonon G, Passananti C, Blandino G, Fanciulli M. Desantis A, et al. Among authors: tonon g. EMBO J. 2015 May 5;34(9):1214-30. doi: 10.15252/embj.201489920. Epub 2015 Mar 14. EMBO J. 2015. PMID: 25770584 Free PMC article.
UTX/KDM6A Loss Enhances the Malignant Phenotype of Multiple Myeloma and Sensitizes Cells to EZH2 inhibition.
Ezponda T, Dupéré-Richer D, Will CM, Small EC, Varghese N, Patel T, Nabet B, Popovic R, Oyer J, Bulic M, Zheng Y, Huang X, Shah MY, Maji S, Riva A, Occhionorelli M, Tonon G, Kelleher N, Keats J, Licht JD. Ezponda T, et al. Among authors: tonon g. Cell Rep. 2017 Oct 17;21(3):628-640. doi: 10.1016/j.celrep.2017.09.078. Cell Rep. 2017. PMID: 29045832 Free PMC article.
Iron increases the susceptibility of multiple myeloma cells to bortezomib.
Campanella A, Santambrogio P, Fontana F, Frenquelli M, Cenci S, Marcatti M, Sitia R, Tonon G, Camaschella C. Campanella A, et al. Among authors: tonon g. Haematologica. 2013 Jun;98(6):971-9. doi: 10.3324/haematol.2012.074872. Epub 2012 Dec 14. Haematologica. 2013. PMID: 23242599 Free PMC article.
Synthetic Lethal Approaches Exploiting DNA Damage in Aggressive Myeloma.
Cottini F, Hideshima T, Suzuki R, Tai YT, Bianchini G, Richardson PG, Anderson KC, Tonon G. Cottini F, et al. Among authors: tonon g. Cancer Discov. 2015 Sep;5(9):972-87. doi: 10.1158/2159-8290.CD-14-0943. Epub 2015 Jun 16. Cancer Discov. 2015. PMID: 26080835 Free PMC article.
HIF-1α regulates the interaction of chronic lymphocytic leukemia cells with the tumor microenvironment.
Valsecchi R, Coltella N, Belloni D, Ponente M, Ten Hacken E, Scielzo C, Scarfò L, Bertilaccio MT, Brambilla P, Lenti E, Martinelli Boneschi F, Brendolan A, Ferrero E, Ferrarini M, Ghia P, Tonon G, Ponzoni M, Caligaris-Cappio F, Bernardi R. Valsecchi R, et al. Among authors: tonon g. Blood. 2016 Apr 21;127(16):1987-97. doi: 10.1182/blood-2015-07-657056. Epub 2016 Jan 29. Blood. 2016. PMID: 26825709 Free PMC article.
197 results