Tonks A - Search Results

1

Protein Kinase C Epsilon Overexpression Is Associated With Poor Patient Outcomes in AML and Promotes Daunorubicin Resistance Through p-Glycoprotein-Mediated Drug Efflux.

Nicholson R, Menezes AC, Azevedo A, Leckenby A, Davies S, Seedhouse C, Gilkes A, Knapper S, Tonks A, Darley RL. Nicholson R, et al. Among authors: tonks a. Front Oncol. 2022 May 30;12:840046. doi: 10.3389/fonc.2022.840046. eCollection 2022. Front Oncol. 2022. PMID: 35707351 Free PMC article.

2

The AML1-ETO fusion gene promotes extensive self-renewal of human primary erythroid cells.

Tonks A, Pearn L, Tonks AJ, Pearce L, Hoy T, Phillips S, Fisher J, Downing JR, Burnett AK, Darley RL. Tonks A, et al. Among authors: tonks aj. Blood. 2003 Jan 15;101(2):624-32. doi: 10.1182/blood-2002-06-1732. Epub 2002 Aug 22. Blood. 2003. PMID: 12393523 Free article.

3

Expression of AML1-ETO in human myelomonocytic cells selectively inhibits granulocytic differentiation and promotes their self-renewal.

Tonks A, Tonks AJ, Pearn L, Pearce L, Hoy T, Couzens S, Fisher J, Burnett AK, Darley RL. Tonks A, et al. Among authors: tonks aj. Leukemia. 2004 Jul;18(7):1238-45. doi: 10.1038/sj.leu.2403396. Leukemia. 2004. PMID: 15152269

4

Optimized retroviral transduction protocol which preserves the primitive subpopulation of human hematopoietic cells.

Tonks A, Tonks AJ, Pearn L, Mohamad Z, Burnett AK, Darley RL. Tonks A, et al. Among authors: tonks aj. Biotechnol Prog. 2005 May-Jun;21(3):953-8. doi: 10.1021/bp0500314. Biotechnol Prog. 2005. PMID: 15932279

5

FUS expression alters the differentiation response to all-trans retinoic acid in NB4 and NB4R2 cells.

Walsby EJ, Gilkes AF, Tonks A, Darley RL, Mills KI. Walsby EJ, et al. Among authors: tonks a. Br J Haematol. 2007 Oct;139(1):94-7. doi: 10.1111/j.1365-2141.2007.06756.x. Br J Haematol. 2007. PMID: 17854312 Free article.

6

Ras-induced reactive oxygen species promote growth factor-independent proliferation in human CD34+ hematopoietic progenitor cells.

Hole PS, Pearn L, Tonks AJ, James PE, Burnett AK, Darley RL, Tonks A. Hole PS, et al. Among authors: tonks a, tonks aj. Blood. 2010 Feb 11;115(6):1238-46. doi: 10.1182/blood-2009-06-222869. Epub 2009 Dec 10. Blood. 2010. PMID: 20007804 Free article.

7

Do reactive oxygen species play a role in myeloid leukemias?

Hole PS, Darley RL, Tonks A. Hole PS, et al. Among authors: tonks a. Blood. 2011 Jun 2;117(22):5816-26. doi: 10.1182/blood-2011-01-326025. Epub 2011 Mar 11. Blood. 2011. PMID: 21398578 Free article. Review.

8

Overproduction of NOX-derived ROS in AML promotes proliferation and is associated with defective oxidative stress signaling.

Hole PS, Zabkiewicz J, Munje C, Newton Z, Pearn L, White P, Marquez N, Hills RK, Burnett AK, Tonks A, Darley RL. Hole PS, et al. Among authors: tonks a. Blood. 2013 Nov 7;122(19):3322-30. doi: 10.1182/blood-2013-04-491944. Epub 2013 Oct 2. Blood. 2013. PMID: 24089327 Free article.

9

The PDK1 master kinase is over-expressed in acute myeloid leukemia and promotes PKC-mediated survival of leukemic blasts.

Zabkiewicz J, Pearn L, Hills RK, Morgan RG, Tonks A, Burnett AK, Darley RL. Zabkiewicz J, et al. Among authors: tonks a. Haematologica. 2014 May;99(5):858-64. doi: 10.3324/haematol.2013.096487. Epub 2013 Dec 13. Haematologica. 2014. PMID: 24334295 Free PMC article.

10

Factors affecting the nuclear localization of β-catenin in normal and malignant tissue.

Morgan RG, Ridsdale J, Tonks A, Darley RL. Morgan RG, et al. Among authors: tonks a. J Cell Biochem. 2014 Aug;115(8):1351-61. doi: 10.1002/jcb.24803. J Cell Biochem. 2014. PMID: 24610469 Review.

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