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mTOR-related synaptic pathology causes autism spectrum disorder-associated functional hyperconnectivity.
Pagani M, Barsotti N, Bertero A, Trakoshis S, Ulysse L, Locarno A, Miseviciute I, De Felice A, Canella C, Supekar K, Galbusera A, Menon V, Tonini R, Deco G, Lombardo MV, Pasqualetti M, Gozzi A. Pagani M, et al. Among authors: tonini r. Nat Commun. 2021 Oct 19;12(1):6084. doi: 10.1038/s41467-021-26131-z. Nat Commun. 2021. PMID: 34667149 Free PMC article.
A light-gated potassium channel for sustained neuronal inhibition.
Alberio L, Locarno A, Saponaro A, Romano E, Bercier V, Albadri S, Simeoni F, Moleri S, Pelucchi S, Porro A, Marcello E, Barsotti N, Kukovetz K, Boender AJ, Contestabile A, Luo S, Moutal A, Ji Y, Romani G, Beltrame M, Del Bene F, Di Luca M, Khanna R, Colecraft HM, Pasqualetti M, Thiel G, Tonini R, Moroni A. Alberio L, et al. Among authors: tonini r. Nat Methods. 2018 Nov;15(11):969-976. doi: 10.1038/s41592-018-0186-9. Epub 2018 Oct 30. Nat Methods. 2018. PMID: 30377377 Free PMC article.
Serotonin depletion causes valproate-responsive manic-like condition and increased hippocampal neuroplasticity that are reversed by stress.
Maddaloni G, Migliarini S, Napolitano F, Giorgi A, Nazzi S, Biasci D, De Felice A, Gritti M, Cavaccini A, Galbusera A, Franceschi S, Lessi F, Ferla M, Aretini P, Mazzanti CM, Tonini R, Gozzi A, Usiello A, Pasqualetti M. Maddaloni G, et al. Among authors: tonini r. Sci Rep. 2018 Aug 7;8(1):11847. doi: 10.1038/s41598-018-30291-2. Sci Rep. 2018. PMID: 30087403 Free PMC article.
Brain-wide Mapping of Endogenous Serotonergic Transmission via Chemogenetic fMRI.
Giorgi A, Migliarini S, Galbusera A, Maddaloni G, Mereu M, Margiani G, Gritti M, Landi S, Trovato F, Bertozzi SM, Armirotti A, Ratto GM, De Luca MA, Tonini R, Gozzi A, Pasqualetti M. Giorgi A, et al. Among authors: tonini r. Cell Rep. 2017 Oct 24;21(4):910-918. doi: 10.1016/j.celrep.2017.09.087. Cell Rep. 2017. PMID: 29069598 Free article.
Serotonergic Signaling Controls Input-Specific Synaptic Plasticity at Striatal Circuits.
Cavaccini A, Gritti M, Giorgi A, Locarno A, Heck N, Migliarini S, Bertero A, Mereu M, Margiani G, Trusel M, Catelani T, Marotta R, De Luca MA, Caboche J, Gozzi A, Pasqualetti M, Tonini R. Cavaccini A, et al. Among authors: tonini r. Neuron. 2018 May 16;98(4):801-816.e7. doi: 10.1016/j.neuron.2018.04.008. Epub 2018 Apr 26. Neuron. 2018. PMID: 29706583 Free article.
LSD1 is an environmental stress-sensitive negative modulator of the glutamatergic synapse.
Longaretti A, Forastieri C, Toffolo E, Caffino L, Locarno A, Misevičiūtė I, Marchesi E, Battistin M, Ponzoni L, Madaschi L, Cambria C, Bonasoni MP, Sala M, Perrone D, Fumagalli F, Bassani S, Antonucci F, Tonini R, Francolini M, Battaglioli E, Rusconi F. Longaretti A, et al. Among authors: tonini r. Neurobiol Stress. 2020 Nov 27;13:100280. doi: 10.1016/j.ynstr.2020.100280. eCollection 2020 Nov. Neurobiol Stress. 2020. PMID: 33457471 Free PMC article.
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