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Structural simplification of bioactive natural products with multicomponent synthesis. 4. 4H-pyrano-[2,3-b]naphthoquinones with anticancer activity.
Magedov IV, Kireev AS, Jenkins AR, Evdokimov NM, Lima DT, Tongwa P, Altig J, Steelant WF, Van slambrouck S, Antipin MY, Kornienko A. Magedov IV, et al. Among authors: tongwa p. Bioorg Med Chem Lett. 2012 Aug 15;22(16):5195-8. doi: 10.1016/j.bmcl.2012.06.073. Epub 2012 Jul 4. Bioorg Med Chem Lett. 2012. PMID: 22819765 Free PMC article.
Three-component synthesis and anticancer evaluation of polycyclic indenopyridines lead to the discovery of a novel indenoheterocycle with potent apoptosis inducing properties.
Manpadi M, Uglinskii PY, Rastogi SK, Cotter KM, Wong YS, Anderson LA, Ortega AJ, Van Slambrouck S, Steelant WF, Rogelj S, Tongwa P, Antipin MY, Magedov IV, Kornienko A. Manpadi M, et al. Among authors: tongwa p. Org Biomol Chem. 2007 Dec 7;5(23):3865-72. doi: 10.1039/b713820b. Epub 2007 Oct 24. Org Biomol Chem. 2007. PMID: 18004468
Structural simplification of bioactive natural products with multicomponent synthesis. 2. antiproliferative and antitubulin activities of pyrano[3,2-c]pyridones and pyrano[3,2-c]quinolones.
Magedov IV, Manpadi M, Ogasawara MA, Dhawan AS, Rogelj S, Van Slambrouck S, Steelant WF, Evdokimov NM, Uglinskii PY, Elias EM, Knee EJ, Tongwa P, Antipin MY, Kornienko A. Magedov IV, et al. Among authors: tongwa p. J Med Chem. 2008 Apr 24;51(8):2561-70. doi: 10.1021/jm701499n. Epub 2008 Mar 25. J Med Chem. 2008. PMID: 18361483 Free PMC article.
Reengineered epipodophyllotoxin.
Magedov IV, Evdokimov NM, Karki M, Peretti AS, Lima DT, Frolova LV, Reisenauer MR, Romero AE, Tongwa P, Fonari A, Altig J, Rogelj S, Antipin MY, Shuster CB, Kornienko A. Magedov IV, et al. Among authors: tongwa p. Chem Commun (Camb). 2012 Oct 28;48(84):10416-8. doi: 10.1039/c2cc35044k. Epub 2012 Sep 17. Chem Commun (Camb). 2012. PMID: 22986348 Free PMC article.
16 results