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Tumor cell-intrinsic PD-1 receptor is a tumor suppressor and mediates resistance to PD-1 blockade therapy.
Wang X, Yang X, Zhang C, Wang Y, Cheng T, Duan L, Tong Z, Tan S, Zhang H, Saw PE, Gu Y, Wang J, Zhang Y, Shang L, Liu Y, Jiang S, Yan B, Li R, Yang Y, Yu J, Chen Y, Gao GF, Ye Q, Gao S. Wang X, et al. Among authors: tong z. Proc Natl Acad Sci U S A. 2020 Mar 24;117(12):6640-6650. doi: 10.1073/pnas.1921445117. Epub 2020 Mar 11. Proc Natl Acad Sci U S A. 2020. PMID: 32161124 Free PMC article.
An unexpected N-terminal loop in PD-1 dominates binding by nivolumab.
Tan S, Zhang H, Chai Y, Song H, Tong Z, Wang Q, Qi J, Wong G, Zhu X, Liu WJ, Gao S, Wang Z, Shi Y, Yang F, Gao GF, Yan J. Tan S, et al. Among authors: tong z. Nat Commun. 2017 Feb 6;8:14369. doi: 10.1038/ncomms14369. Nat Commun. 2017. PMID: 28165004 Free PMC article.
Neutralization mechanism of human monoclonal antibodies against Rift Valley fever virus.
Wang Q, Ma T, Wu Y, Chen Z, Zeng H, Tong Z, Gao F, Qi J, Zhao Z, Chai Y, Yang H, Wong G, Bi Y, Wu L, Shi R, Yang M, Song J, Jiang H, An Z, Wang J, Yilma TD, Shi Y, Liu WJ, Liang M, Qin C, Gao GF, Yan J. Wang Q, et al. Among authors: tong z. Nat Microbiol. 2019 Jul;4(7):1231-1241. doi: 10.1038/s41564-019-0411-z. Epub 2019 Apr 1. Nat Microbiol. 2019. PMID: 30936489
A human neutralizing antibody targets the receptor-binding site of SARS-CoV-2.
Shi R, Shan C, Duan X, Chen Z, Liu P, Song J, Song T, Bi X, Han C, Wu L, Gao G, Hu X, Zhang Y, Tong Z, Huang W, Liu WJ, Wu G, Zhang B, Wang L, Qi J, Feng H, Wang FS, Wang Q, Gao GF, Yuan Z, Yan J. Shi R, et al. Among authors: tong z. Nature. 2020 Aug;584(7819):120-124. doi: 10.1038/s41586-020-2381-y. Epub 2020 May 26. Nature. 2020. PMID: 32454512
2,604 results