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The tetraspanin Tspan15 is an essential subunit of an ADAM10 scissor complex.
Koo CZ, Harrison N, Noy PJ, Szyroka J, Matthews AL, Hsia HE, Müller SA, Tüshaus J, Goulding J, Willis K, Apicella C, Cragoe B, Davis E, Keles M, Malinova A, McFarlane TA, Morrison PR, Nguyen HTH, Sykes MC, Ahmed H, Di Maio A, Seipold L, Saftig P, Cull E, Pliotas C, Rubinstein E, Poulter NS, Briddon SJ, Holliday ND, Lichtenthaler SF, Tomlinson MG. Koo CZ, et al. Among authors: tomlinson mg. J Biol Chem. 2020 Sep 4;295(36):12822-12839. doi: 10.1074/jbc.RA120.012601. Epub 2020 Feb 28. J Biol Chem. 2020. PMID: 32111735 Free PMC article.
TspanC8 Tetraspanins and A Disintegrin and Metalloprotease 10 (ADAM10) Interact via Their Extracellular Regions: EVIDENCE FOR DISTINCT BINDING MECHANISMS FOR DIFFERENT TspanC8 PROTEINS.
Noy PJ, Yang J, Reyat JS, Matthews AL, Charlton AE, Furmston J, Rogers DA, Rainger GE, Tomlinson MG. Noy PJ, et al. Among authors: tomlinson mg. J Biol Chem. 2016 Feb 12;291(7):3145-57. doi: 10.1074/jbc.M115.703058. Epub 2015 Dec 14. J Biol Chem. 2016. PMID: 26668317 Free PMC article.
Scissor sisters: regulation of ADAM10 by the TspanC8 tetraspanins.
Matthews AL, Szyroka J, Collier R, Noy PJ, Tomlinson MG. Matthews AL, et al. Among authors: tomlinson mg. Biochem Soc Trans. 2017 Jun 15;45(3):719-730. doi: 10.1042/BST20160290. Biochem Soc Trans. 2017. PMID: 28620033 Free PMC article. Review.
Tspan18 is a novel regulator of thrombo-inflammation.
Gavin RL, Koo CZ, Tomlinson MG. Gavin RL, et al. Among authors: tomlinson mg. Med Microbiol Immunol. 2020 Aug;209(4):553-564. doi: 10.1007/s00430-020-00678-y. Epub 2020 May 23. Med Microbiol Immunol. 2020. PMID: 32447449 Free PMC article. Review.
69 results