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EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells.
Kleer CG, Cao Q, Varambally S, Shen R, Ota I, Tomlins SA, Ghosh D, Sewalt RG, Otte AP, Hayes DF, Sabel MS, Livant D, Weiss SJ, Rubin MA, Chinnaiyan AM. Kleer CG, et al. Among authors: tomlins sa. Proc Natl Acad Sci U S A. 2003 Sep 30;100(20):11606-11. doi: 10.1073/pnas.1933744100. Epub 2003 Sep 19. Proc Natl Acad Sci U S A. 2003. PMID: 14500907 Free PMC article.
Repression of E-cadherin by the polycomb group protein EZH2 in cancer.
Cao Q, Yu J, Dhanasekaran SM, Kim JH, Mani RS, Tomlins SA, Mehra R, Laxman B, Cao X, Yu J, Kleer CG, Varambally S, Chinnaiyan AM. Cao Q, et al. Among authors: tomlins sa. Oncogene. 2008 Dec 11;27(58):7274-84. doi: 10.1038/onc.2008.333. Epub 2008 Sep 22. Oncogene. 2008. PMID: 18806826 Free PMC article.
AGTR1 overexpression defines a subset of breast cancer and confers sensitivity to losartan, an AGTR1 antagonist.
Rhodes DR, Ateeq B, Cao Q, Tomlins SA, Mehra R, Laxman B, Kalyana-Sundaram S, Lonigro RJ, Helgeson BE, Bhojani MS, Rehemtulla A, Kleer CG, Hayes DF, Lucas PC, Varambally S, Chinnaiyan AM. Rhodes DR, et al. Among authors: tomlins sa. Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10284-9. doi: 10.1073/pnas.0900351106. Epub 2009 Jun 1. Proc Natl Acad Sci U S A. 2009. PMID: 19487683 Free PMC article.
262 results