Tomesch J - Search Results

1

Magic Angle Spinning NMR for Reaction Monitoring and Structure Determination of Molecules Attached to Multipin Crowns.

Chin J, Fell B, Shapiro MJ, Tomesch J, Wareing JR, Bray AM. Chin J, et al. Among authors: tomesch j. J Org Chem. 1997 Feb 7;62(3):538-539. doi: 10.1021/jo961590f. J Org Chem. 1997. PMID: 11671446

2

Synthesis of 1-O-(15-carboxypentadecyl)-2-O-acetyl-sn-glycero-3-phosphorylcholine as a potential platelet activating factor (PAF) hapten.

Prashad M, Tomesch JC, Wareing JR. Prashad M, et al. Among authors: tomesch jc. Chem Phys Lipids. 1990 Mar;53(1):121-6. doi: 10.1016/0009-3084(90)90140-m. Chem Phys Lipids. 1990. PMID: 2354543 No abstract available.

3

Chemistry and pharmacology of PAF antagonists. Evaluation of changes at potential metabolism sites on activity and duration of activity.

Handley DA, Houlihan WJ, Tomesch JC, Farley C, Deacon RW, Koletar JM, Prashad M, Hughes JW, Jaeggi C. Handley DA, et al. Among authors: tomesch jc. Adv Prostaglandin Thromboxane Leukot Res. 1989;19:367-70. Adv Prostaglandin Thromboxane Leukot Res. 1989. PMID: 2546390 No abstract available.

4

Inhibition of PAF-induced systemic responses in the rat, guinea pig, dog and primate by the receptor antagonist SRI 63-441.

Handley DA, Tomesch JC, Saunders RN. Handley DA, et al. Among authors: tomesch jc. Thromb Haemost. 1986 Aug 20;56(1):40-4. Thromb Haemost. 1986. PMID: 3775689

5

In vitro and in vivo pharmacological profiles of the PAF receptor antagonist SRI 63-675.

Handley DA, Van Valen RG, Winslow CM, Tomesch JC, Saunders RN. Handley DA, et al. Among authors: tomesch jc. Thromb Haemost. 1987 Apr 7;57(2):187-90. Thromb Haemost. 1987. PMID: 3037718

6

Biological properties of the antagonist SRI 63-441 in the PAF and endotoxin models of hypotension in the rat and dog.

Handley DA, Van Valen RG, Tomesch JC, Melden MK, Jaffe JM, Ballard FH, Saunders RN. Handley DA, et al. Among authors: tomesch jc. Immunopharmacology. 1987 Apr;13(2):125-32. doi: 10.1016/0162-3109(87)90049-x. Immunopharmacology. 1987. PMID: 3597060

7

Functional profile of a novel modulator of serotonin, dopamine, and glutamate neurotransmission.

Snyder GL, Vanover KE, Zhu H, Miller DB, O'Callaghan JP, Tomesch J, Li P, Zhang Q, Krishnan V, Hendrick JP, Nestler EJ, Davis RE, Wennogle LP, Mates S. Snyder GL, et al. Among authors: tomesch j. Psychopharmacology (Berl). 2015 Feb;232(3):605-21. doi: 10.1007/s00213-014-3704-1. Epub 2014 Aug 15. Psychopharmacology (Berl). 2015. PMID: 25120104 Free PMC article.

8

Discovery of a tetracyclic quinoxaline derivative as a potent and orally active multifunctional drug candidate for the treatment of neuropsychiatric and neurological disorders.

Li P, Zhang Q, Robichaud AJ, Lee T, Tomesch J, Yao W, Beard JD, Snyder GL, Zhu H, Peng Y, Hendrick JP, Vanover KE, Davis RE, Mates S, Wennogle LP. Li P, et al. Among authors: tomesch j. J Med Chem. 2014 Mar 27;57(6):2670-82. doi: 10.1021/jm401958n. Epub 2014 Mar 5. J Med Chem. 2014. PMID: 24559051

9

Discovery of novel alpha7 nicotinic receptor antagonists.

Peng Y, Zhang Q, Snyder GL, Zhu H, Yao W, Tomesch J, Papke RL, O'Callaghan JP, Welsh WJ, Wennogle LP. Peng Y, et al. Among authors: tomesch j. Bioorg Med Chem Lett. 2010 Aug 15;20(16):4825-30. doi: 10.1016/j.bmcl.2010.06.103. Epub 2010 Jun 25. Bioorg Med Chem Lett. 2010. PMID: 20638843 Free PMC article.

10

Nerve agent exposure elicits site-specific changes in protein phosphorylation in mouse brain.

Zhu H, O'Brien JJ, O'Callaghan JP, Miller DB, Zhang Q, Rana M, Tsui T, Peng Y, Tomesch J, Hendrick JP, Wennogle LP, Snyder GL. Zhu H, et al. Among authors: tomesch j. Brain Res. 2010 Jun 25;1342:11-23. doi: 10.1016/j.brainres.2010.04.034. Epub 2010 Apr 25. Brain Res. 2010. PMID: 20423708 Free PMC article.

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