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A non-hallucinogenic psychedelic analogue with therapeutic potential.
Cameron LP, Tombari RJ, Lu J, Pell AJ, Hurley ZQ, Ehinger Y, Vargas MV, McCarroll MN, Taylor JC, Myers-Turnbull D, Liu T, Yaghoobi B, Laskowski LJ, Anderson EI, Zhang G, Viswanathan J, Brown BM, Tjia M, Dunlap LE, Rabow ZT, Fiehn O, Wulff H, McCorvy JD, Lein PJ, Kokel D, Ron D, Peters J, Zuo Y, Olson DE. Cameron LP, et al. Among authors: tombari rj. Nature. 2021 Jan;589(7842):474-479. doi: 10.1038/s41586-020-3008-z. Epub 2020 Dec 9. Nature. 2021. PMID: 33299186 Free PMC article.
Ex Vivo Analysis of Tryptophan Metabolism Using 19F NMR.
Tombari RJ, Saunders CM, Wu CY, Dunlap LE, Tantillo DJ, Olson DE. Tombari RJ, et al. ACS Chem Biol. 2019 Sep 20;14(9):1866-1873. doi: 10.1021/acschembio.9b00548. Epub 2019 Aug 26. ACS Chem Biol. 2019. PMID: 31449387 Free PMC article.
Reconsidering the Structure of Serlyticin-A.
Tsui KY, Tombari RJ, Olson DE, Tantillo DJ. Tsui KY, et al. Among authors: tombari rj. J Nat Prod. 2019 Dec 27;82(12):3464-3468. doi: 10.1021/acs.jnatprod.9b00859. Epub 2019 Dec 16. J Nat Prod. 2019. PMID: 31840986 Free PMC article.
Identification of Psychoplastogenic N,N-Dimethylaminoisotryptamine (isoDMT) Analogues through Structure-Activity Relationship Studies.
Dunlap LE, Azinfar A, Ly C, Cameron LP, Viswanathan J, Tombari RJ, Myers-Turnbull D, Taylor JC, Grodzki AC, Lein PJ, Kokel D, Olson DE. Dunlap LE, et al. Among authors: tombari rj. J Med Chem. 2020 Feb 13;63(3):1142-1155. doi: 10.1021/acs.jmedchem.9b01404. Epub 2020 Jan 24. J Med Chem. 2020. PMID: 31977208 Free PMC article.
A Modular Approach to Arylazo-1,2,3-triazole Photoswitches.
Tuck JR, Tombari RJ, Yardeny N, Olson DE. Tuck JR, et al. Among authors: tombari rj. Org Lett. 2021 Jun 4;23(11):4305-4310. doi: 10.1021/acs.orglett.1c01230. Epub 2021 May 21. Org Lett. 2021. PMID: 34019429 Free PMC article.
A Redox Isomerization Strategy for Accessing Modular Azobenzene Photoswitches with Near Quantitative Bidirectional Photoconversion.
Zhu JS, Larach JM, Tombari RJ, Gingrich PW, Bode SR, Tuck JR, Warren HT, Son JH, Duim WC, Fettinger JC, Haddadin MJ, Tantillo DJ, Kurth MJ, Olson DE. Zhu JS, et al. Among authors: tombari rj. Org Lett. 2019 Nov 1;21(21):8765-8770. doi: 10.1021/acs.orglett.9b03387. Epub 2019 Oct 22. Org Lett. 2019. PMID: 31638403 Free PMC article.