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Page 1
Single-cell atlas of human liver development reveals pathways directing hepatic cell fates.
Wesley BT, Ross ADB, Muraro D, Miao Z, Saxton S, Tomaz RA, Morell CM, Ridley K, Zacharis ED, Petrus-Reurer S, Kraiczy J, Mahbubani KT, Brown S, Garcia-Bernardo J, Alsinet C, Gaffney D, Horsfall D, Tysoe OC, Botting RA, Stephenson E, Popescu DM, MacParland S, Bader G, McGilvray ID, Ortmann D, Sampaziotis F, Saeb-Parsy K, Haniffa M, Stevens KR, Zilbauer M, Teichmann SA, Vallier L. Wesley BT, et al. Among authors: tomaz ra. Nat Cell Biol. 2022 Oct;24(10):1487-1498. doi: 10.1038/s41556-022-00989-7. Epub 2022 Sep 15. Nat Cell Biol. 2022. PMID: 36109670
Generation of functional hepatocytes by forward programming with nuclear receptors.
Tomaz RA, Zacharis ED, Bachinger F, Wurmser A, Yamamoto D, Petrus-Reurer S, Morell CM, Dziedzicka D, Wesley BT, Geti I, Segeritz CP, de Brito MC, Chhatriwala M, Ortmann D, Saeb-Parsy K, Vallier L. Tomaz RA, et al. Elife. 2022 Aug 12;11:e71591. doi: 10.7554/eLife.71591. Elife. 2022. PMID: 35959725 Free PMC article.
Method to Synchronize Cell Cycle of Human Pluripotent Stem Cells without Affecting Their Fundamental Characteristics.
Yiangou L, Grandy RA, Morell CM, Tomaz RA, Osnato A, Kadiwala J, Muraro D, Garcia-Bernardo J, Nakanoh S, Bernard WG, Ortmann D, McCarthy DJ, Simonic I, Sinha S, Vallier L. Yiangou L, et al. Among authors: tomaz ra. Stem Cell Reports. 2019 Jan 8;12(1):165-179. doi: 10.1016/j.stemcr.2018.11.020. Epub 2018 Dec 27. Stem Cell Reports. 2019. PMID: 30595546 Free PMC article.
Regional Differences in Human Biliary Tissues and Corresponding In Vitro-Derived Organoids.
Rimland CA, Tilson SG, Morell CM, Tomaz RA, Lu WY, Adams SE, Georgakopoulos N, Otaizo-Carrasquero F, Myers TG, Ferdinand JR, Gieseck RL 3rd, Sampaziotis F, Tysoe OC, Ross A, Kraiczy JM, Wesley B, Muraro D, Zilbauer M, Oniscu GC, Hannan NRF, Forbes SJ, Saeb-Parsy K, Wynn TA, Vallier L. Rimland CA, et al. Among authors: tomaz ra. Hepatology. 2021 Jan;73(1):247-267. doi: 10.1002/hep.31252. Hepatology. 2021. PMID: 32222998 Free PMC article.
Modeling Disease with Human Inducible Pluripotent Stem Cells.
Grandy R, Tomaz RA, Vallier L. Grandy R, et al. Among authors: tomaz ra. Annu Rev Pathol. 2019 Jan 24;14:449-468. doi: 10.1146/annurev-pathol-020117-043634. Epub 2018 Oct 24. Annu Rev Pathol. 2019. PMID: 30355153 Review.
Naive Pluripotent Stem Cells Exhibit Phenotypic Variability that Is Driven by Genetic Variation.
Ortmann D, Brown S, Czechanski A, Aydin S, Muraro D, Huang Y, Tomaz RA, Osnato A, Canu G, Wesley BT, Skelly DA, Stegle O, Choi T, Churchill GA, Baker CL, Rugg-Gunn PJ, Munger SC, Reinholdt LG, Vallier L. Ortmann D, et al. Among authors: tomaz ra. Cell Stem Cell. 2020 Sep 3;27(3):470-481.e6. doi: 10.1016/j.stem.2020.07.019. Epub 2020 Aug 13. Cell Stem Cell. 2020. PMID: 32795399 Free PMC article.
3D human liver tissue from pluripotent stem cells displays stable phenotype in vitro and supports compromised liver function in vivo.
Rashidi H, Luu NT, Alwahsh SM, Ginai M, Alhaque S, Dong H, Tomaz RA, Vernay B, Vigneswara V, Hallett JM, Chandrashekran A, Dhawan A, Vallier L, Bradley M, Callanan A, Forbes SJ, Newsome PN, Hay DC. Rashidi H, et al. Among authors: tomaz ra. Arch Toxicol. 2018 Oct;92(10):3117-3129. doi: 10.1007/s00204-018-2280-2. Epub 2018 Aug 28. Arch Toxicol. 2018. PMID: 30155720 Free PMC article.
GDF15 mediates the effects of metformin on body weight and energy balance.
Coll AP, Chen M, Taskar P, Rimmington D, Patel S, Tadross JA, Cimino I, Yang M, Welsh P, Virtue S, Goldspink DA, Miedzybrodzka EL, Konopka AR, Esponda RR, Huang JT, Tung YCL, Rodriguez-Cuenca S, Tomaz RA, Harding HP, Melvin A, Yeo GSH, Preiss D, Vidal-Puig A, Vallier L, Nair KS, Wareham NJ, Ron D, Gribble FM, Reimann F, Sattar N, Savage DB, Allan BB, O'Rahilly S. Coll AP, et al. Among authors: tomaz ra. Nature. 2020 Feb;578(7795):444-448. doi: 10.1038/s41586-019-1911-y. Epub 2019 Dec 25. Nature. 2020. PMID: 31875646 Free PMC article. Clinical Trial.
Publisher Correction: GDF15 mediates the effects of metformin on body weight and energy balance.
Coll AP, Chen M, Taskar P, Rimmington D, Patel S, Tadross JA, Cimino I, Yang M, Welsh P, Virtue S, Goldspink DA, Miedzybrodzka EL, Konopka AR, Esponda RR, Huang JT, Tung YCL, Rodriguez-Cuenca S, Tomaz RA, Harding HP, Melvin A, Yeo GSH, Preiss D, Vidal-Puig A, Vallier L, Nair KS, Wareham NJ, Ron D, Gribble FM, Reimann F, Sattar N, Savage DB, Allan BB, O'Rahilly S. Coll AP, et al. Among authors: tomaz ra. Nature. 2020 Feb;578(7796):E24. doi: 10.1038/s41586-020-2031-4. Nature. 2020. PMID: 32051582
18 results