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Page 1
A candidate antibody drug for prevention of malaria.
Williams KL, Guerrero S, Flores-Garcia Y, Kim D, Williamson KS, Siska C, Smidt P, Jepson SZ, Li K, Dennison SM, Mathis-Torres S, Chen X, Wille-Reece U, MacGill RS, Walker M, Jongert E, King CR, Ockenhouse C, Glanville J, Moon JE, Regules JA, Tan YC, Cavet G, Lippow SM, Robinson WH, Dutta S, Tomaras GD, Zavala F, Ketchem RR, Emerling DE. Williams KL, et al. Among authors: tomaras gd. Nat Med. 2024 Jan;30(1):117-129. doi: 10.1038/s41591-023-02659-z. Epub 2024 Jan 2. Nat Med. 2024. PMID: 38167935 Free PMC article.
Prolonged exposure of the HIV-1 gp41 membrane proximal region with L669S substitution.
Shen X, Dennison SM, Liu P, Gao F, Jaeger F, Montefiori DC, Verkoczy L, Haynes BF, Alam SM, Tomaras GD. Shen X, et al. Among authors: tomaras gd. Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):5972-7. doi: 10.1073/pnas.0912381107. Epub 2010 Mar 15. Proc Natl Acad Sci U S A. 2010. PMID: 20231447 Free PMC article.
Differential reactivity of germ line allelic variants of a broadly neutralizing HIV-1 antibody to a gp41 fusion intermediate conformation.
Alam SM, Liao HX, Dennison SM, Jaeger F, Parks R, Anasti K, Foulger A, Donathan M, Lucas J, Verkoczy L, Nicely N, Tomaras GD, Kelsoe G, Chen B, Kepler TB, Haynes BF. Alam SM, et al. Among authors: tomaras gd. J Virol. 2011 Nov;85(22):11725-31. doi: 10.1128/JVI.05680-11. Epub 2011 Sep 14. J Virol. 2011. PMID: 21917975 Free PMC article.
Qualified Biolayer Interferometry Avidity Measurements Distinguish the Heterogeneity of Antibody Interactions with Plasmodium falciparum Circumsporozoite Protein Antigens.
Dennison SM, Reichartz M, Seaton KE, Dutta S, Wille-Reece U, Hill AVS, Ewer KJ, Rountree W, Sarzotti-Kelsoe M, Ozaki DA, Alam SM, Tomaras GD. Dennison SM, et al. Among authors: tomaras gd. J Immunol. 2018 Aug 15;201(4):1315-1326. doi: 10.4049/jimmunol.1800323. Epub 2018 Jul 13. J Immunol. 2018. PMID: 30006374 Free PMC article.
Framework Mutations of the 10-1074 bnAb Increase Conformational Stability, Manufacturability, and Stability While Preserving Full Neutralization Activity.
Kerwin BA, Bennett C, Brodsky Y, Clark R, Floyd JA, Gillespie A, Mayer BT, McClure M, Siska C, Seaman MS, Seaton KE, Shaver J, Tomaras GD, Yates NL, Ketchem RR. Kerwin BA, et al. Among authors: tomaras gd. J Pharm Sci. 2020 Jan;109(1):233-246. doi: 10.1016/j.xphs.2019.07.009. Epub 2019 Jul 23. J Pharm Sci. 2020. PMID: 31348937 Free PMC article.
IgA and IgG1 Specific to Vi Polysaccharide of Salmonella Typhi Correlate With Protection Status in a Typhoid Fever Controlled Human Infection Model.
Dahora LC, Jin C, Spreng RL, Feely F, Mathura R, Seaton KE, Zhang L, Hill J, Jones E, Alam SM, Dennison SM, Pollard AJ, Tomaras GD. Dahora LC, et al. Among authors: tomaras gd. Front Immunol. 2019 Nov 1;10:2582. doi: 10.3389/fimmu.2019.02582. eCollection 2019. Front Immunol. 2019. PMID: 31781100 Free PMC article. Clinical Trial.
Vi-specific serological correlates of protection for typhoid fever.
Jin C, Hill J, Gunn BM, Yu WH, Dahora LC, Jones E, Johnson M, Gibani MM, Spreng RL, Alam SM, Nebykova A, Juel HB, Dennison SM, Seaton KE, Fallon JK, Tomaras GD, Alter G, Pollard AJ. Jin C, et al. Among authors: tomaras gd. J Exp Med. 2021 Feb 1;218(2):e20201116. doi: 10.1084/jem.20201116. J Exp Med. 2021. PMID: 33180929 Free PMC article. Clinical Trial.
In vitro and in vivo inhibition of malaria parasite infection by monoclonal antibodies against Plasmodium falciparum circumsporozoite protein (CSP).
Livingstone MC, Bitzer AA, Giri A, Luo K, Sankhala RS, Choe M, Zou X, Dennison SM, Li Y, Washington W, Ngauy V, Tomaras GD, Joyce MG, Batchelor AH, Dutta S. Livingstone MC, et al. Among authors: tomaras gd. Sci Rep. 2021 Mar 5;11(1):5318. doi: 10.1038/s41598-021-84622-x. Sci Rep. 2021. PMID: 33674699 Free PMC article.
Comprehensive Data Integration Approach to Assess Immune Responses and Correlates of RTS,S/AS01-Mediated Protection From Malaria Infection in Controlled Human Malaria Infection Trials.
Young WC, Carpp LN, Chaudhury S, Regules JA, Bergmann-Leitner ES, Ockenhouse C, Wille-Reece U, deCamp AC, Hughes E, Mahoney C, Pallikkuth S, Pahwa S, Dennison SM, Mudrak SV, Alam SM, Seaton KE, Spreng RL, Fallon J, Michell A, Ulloa-Montoya F, Coccia M, Jongert E, Alter G, Tomaras GD, Gottardo R. Young WC, et al. Among authors: tomaras gd. Front Big Data. 2021 Jun 15;4:672460. doi: 10.3389/fdata.2021.672460. eCollection 2021. Front Big Data. 2021. PMID: 34212134 Free PMC article.
343 results