Tomar T - Search Results

1

Integrative Kinome Profiling Identifies mTORC1/2 Inhibition as Treatment Strategy in Ovarian Clear Cell Carcinoma.

Caumanns JJ, Berns K, Wisman GBA, Fehrmann RSN, Tomar T, Klip H, Meersma GJ, Hijmans EM, Gennissen AMC, Duiker EW, Weening D, Itamochi H, Kluin RJC, Reyners AKL, Birrer MJ, Salvesen HB, Vergote I, van Nieuwenhuysen E, Brenton J, Braicu EI, Kupryjanczyk J, Spiewankiewicz B, Mittempergher L, Bernards R, van der Zee AGJ, de Jong S. Caumanns JJ, et al. Among authors: tomar t. Clin Cancer Res. 2018 Aug 15;24(16):3928-3940. doi: 10.1158/1078-0432.CCR-17-3060. Epub 2018 Apr 23. Clin Cancer Res. 2018. PMID: 29685880 Free PMC article.

2

Genome-wide methylation profiling of ovarian cancer patient-derived xenografts treated with the demethylating agent decitabine identifies novel epigenetically regulated genes and pathways.

Tomar T, de Jong S, Alkema NG, Hoekman RL, Meersma GJ, Klip HG, van der Zee AG, Wisman GB. Tomar T, et al. Genome Med. 2016 Oct 20;8(1):107. doi: 10.1186/s13073-016-0361-5. Genome Med. 2016. PMID: 27765068 Free PMC article.

3

Checkpoint kinase 2 (Chk2) supports sensitivity to platinum-based treatment in high grade serous ovarian cancer.

Alkema NG, Tomar T, van der Zee AG, Everts M, Meersma GJ, Hollema H, de Jong S, van Vugt MA, Wisman GB. Alkema NG, et al. Among authors: tomar t. Gynecol Oncol. 2014 Jun;133(3):591-8. doi: 10.1016/j.ygyno.2014.03.557. Epub 2014 Mar 20. Gynecol Oncol. 2014. PMID: 24657486

4

Biobanking of patient and patient-derived xenograft ovarian tumour tissue: efficient preservation with low and high fetal calf serum based methods.

Alkema NG, Tomar T, Duiker EW, Jan Meersma G, Klip H, van der Zee AG, Wisman GB, de Jong S. Alkema NG, et al. Among authors: tomar t. Sci Rep. 2015 Oct 6;5:14495. doi: 10.1038/srep14495. Sci Rep. 2015. PMID: 26440065 Free PMC article.

5

Methylome analysis of extreme chemoresponsive patients identifies novel markers of platinum sensitivity in high-grade serous ovarian cancer.

Tomar T, Alkema NG, Schreuder L, Meersma GJ, de Meyer T, van Criekinge W, Klip HG, Fiegl H, van Nieuwenhuysen E, Vergote I, Widschwendter M, Schuuring E, van der Zee AGJ, de Jong S, Wisman GBA. Tomar T, et al. BMC Med. 2017 Jun 23;15(1):116. doi: 10.1186/s12916-017-0870-0. BMC Med. 2017. PMID: 28641578 Free PMC article.

6

Combined Inhibition of SHP2 and MEK Is Effective in Models of NF1-Deficient Malignant Peripheral Nerve Sheath Tumors.

Wang J, Pollard K, Allen AN, Tomar T, Pijnenburg D, Yao Z, Rodriguez FJ, Pratilas CA. Wang J, et al. Among authors: tomar t. Cancer Res. 2020 Dec 1;80(23):5367-5379. doi: 10.1158/0008-5472.CAN-20-1365. Epub 2020 Oct 8. Cancer Res. 2020. PMID: 33032988 Free PMC article.

7

Kinome Array Profiling of Patient-Derived Pancreatic Ductal Adenocarcinoma Identifies Differentially Active Protein Tyrosine Kinases.

Creeden JF, Alganem K, Imami AS, Brunicardi FC, Liu SH, Shukla R, Tomar T, Naji F, McCullumsmith RE. Creeden JF, et al. Among authors: tomar t. Int J Mol Sci. 2020 Nov 17;21(22):8679. doi: 10.3390/ijms21228679. Int J Mol Sci. 2020. PMID: 33213062 Free PMC article.

8

Antibody-free LC-MS/MS quantification of rhTRAIL in human and mouse serum.

Wilffert D, Reis CR, Hermans J, Govorukhina N, Tomar T, de Jong S, Quax WJ, van de Merbel NC, Bischoff R. Wilffert D, et al. Among authors: tomar t. Anal Chem. 2013 Nov 19;85(22):10754-60. doi: 10.1021/ac4017902. Epub 2013 Nov 1. Anal Chem. 2013. PMID: 24125577

9

Hypoxia enhances migration and invasion in glioblastoma by promoting a mesenchymal shift mediated by the HIF1α-ZEB1 axis.

Joseph JV, Conroy S, Pavlov K, Sontakke P, Tomar T, Eggens-Meijer E, Balasubramaniyan V, Wagemakers M, den Dunnen WF, Kruyt FA. Joseph JV, et al. Among authors: tomar t. Cancer Lett. 2015 Apr 1;359(1):107-16. doi: 10.1016/j.canlet.2015.01.010. Epub 2015 Jan 12. Cancer Lett. 2015. PMID: 25592037 Free article.

10

TGF-β is an inducer of ZEB1-dependent mesenchymal transdifferentiation in glioblastoma that is associated with tumor invasion.

Joseph JV, Conroy S, Tomar T, Eggens-Meijer E, Bhat K, Copray S, Walenkamp AM, Boddeke E, Balasubramanyian V, Wagemakers M, den Dunnen WF, Kruyt FA. Joseph JV, et al. Among authors: tomar t. Cell Death Dis. 2014 Oct 2;5(10):e1443. doi: 10.1038/cddis.2014.395. Cell Death Dis. 2014. PMID: 25275602 Free PMC article.

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