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Adipocyte Precursor-Derived NRG1 Promotes Resistance to FGFR Inhibition in Urothelial Carcinoma.
Hosni S, Kilian V, Klümper N, Gabbia D, Sieckmann K, Corvino D, Winkler A, Saponaro M, Wörsdörfer K, Schmidt D, Hahn O, Zanotto I, Bertlich M, Toma M, Bald T, Eckstein M, Hölzel M, Geyer M, Ritter M, Wachten D, De Martin S, Alajati A. Hosni S, et al. Among authors: toma m. Cancer Res. 2024 Mar 4;84(5):725-740. doi: 10.1158/0008-5472.CAN-23-1398. Cancer Res. 2024. PMID: 38175774 Free PMC article.
The N6 -methyladenosine (m6 A) erasers alkylation repair homologue 5 (ALKBH5) and fat mass and obesity-associated protein (FTO) are prognostic biomarkers in patients with clear cell renal carcinoma.
Strick A, von Hagen F, Gundert L, Klümper N, Tolkach Y, Schmidt D, Kristiansen G, Toma M, Ritter M, Ellinger J. Strick A, et al. Among authors: toma m. BJU Int. 2020 Apr;125(4):617-624. doi: 10.1111/bju.15019. Epub 2020 Feb 17. BJU Int. 2020. PMID: 31985880
LAG3 (LAG-3, CD223) DNA methylation correlates with LAG3 expression by tumor and immune cells, immune cell infiltration, and overall survival in clear cell renal cell carcinoma.
Klümper N, Ralser DJ, Bawden EG, Landsberg J, Zarbl R, Kristiansen G, Toma M, Ritter M, Hölzel M, Ellinger J, Dietrich D. Klümper N, et al. Among authors: toma m. J Immunother Cancer. 2020 Mar;8(1):e000552. doi: 10.1136/jitc-2020-000552. J Immunother Cancer. 2020. PMID: 32234847 Free PMC article.
Cultivation of Clear Cell Renal Cell Carcinoma Patient-Derived Organoids in an Air-Liquid Interface System as a Tool for Studying Individualized Therapy.
Esser LK, Branchi V, Leonardelli S, Pelusi N, Simon AG, Klümper N, Ellinger J, Hauser S, Gonzalez-Carmona MA, Ritter M, Kristiansen G, Schorle H, Hölzel M, Toma MI. Esser LK, et al. Among authors: toma mi. Front Oncol. 2020 Sep 22;10:1775. doi: 10.3389/fonc.2020.01775. eCollection 2020. Front Oncol. 2020. PMID: 33072556 Free PMC article.
N6 -Methyladenosine (m6 A) readers are dysregulated in renal cell carcinoma.
von Hagen F, Gundert L, Strick A, Klümper N, Schmidt D, Kristiansen G, Tolkach Y, Toma M, Ritter M, Ellinger J. von Hagen F, et al. Among authors: toma m. Mol Carcinog. 2021 May;60(5):354-362. doi: 10.1002/mc.23297. Epub 2021 Mar 23. Mol Carcinog. 2021. PMID: 33755994
CTLA4 promoter hypomethylation is a negative prognostic biomarker at initial diagnosis but predicts response and favorable outcome to anti-PD-1 based immunotherapy in clear cell renal cell carcinoma.
Klümper N, Ralser DJ, Zarbl R, Schlack K, Schrader AJ, Rehlinghaus M, Hoffmann MJ, Niegisch G, Uhlig A, Trojan L, Steinestel J, Steinestel K, Wirtz RM, Sikic D, Eckstein M, Kristiansen G, Toma M, Hölzel M, Ritter M, Strieth S, Ellinger J, Dietrich D. Klümper N, et al. Among authors: toma m. J Immunother Cancer. 2021 Aug;9(8):e002949. doi: 10.1136/jitc-2021-002949. J Immunother Cancer. 2021. PMID: 34446578 Free PMC article.
540 results