Tomé S - Search Results

1

Restoring brain cholesterol turnover improves autophagy and has therapeutic potential in mouse models of spinocerebellar ataxia.

Nóbrega C, Mendonça L, Marcelo A, Lamazière A, Tomé S, Despres G, Matos CA, Mechmet F, Langui D, den Dunnen W, de Almeida LP, Cartier N, Alves S. Nóbrega C, et al. Among authors: tome s. Acta Neuropathol. 2019 Nov;138(5):837-858. doi: 10.1007/s00401-019-02019-7. Epub 2019 Jun 14. Acta Neuropathol. 2019. PMID: 31197505

2

Ibuprofen enhances synaptic function and neural progenitors proliferation markers and improves neuropathology and motor coordination in Machado-Joseph disease models.

Mendonça LS, Nóbrega C, Tavino S, Brinkhaus M, Matos C, Tomé S, Moreira R, Henriques D, Kaspar BK, Pereira de Almeida L. Mendonça LS, et al. Among authors: tome s. Hum Mol Genet. 2019 Nov 15;28(22):3691-3703. doi: 10.1093/hmg/ddz097. Hum Mol Genet. 2019. PMID: 31127937

3

Distinct molecular patterns of TDP-43 pathology in Alzheimer's disease: relationship with clinical phenotypes.

Tomé SO, Vandenberghe R, Ospitalieri S, Van Schoor E, Tousseyn T, Otto M, von Arnim CAF, Thal DR. Tomé SO, et al. Acta Neuropathol Commun. 2020 Apr 29;8(1):61. doi: 10.1186/s40478-020-00934-5. Acta Neuropathol Commun. 2020. PMID: 32349792 Free PMC article.

4

TDP-43 interacts with pathological τ protein in Alzheimer's disease.

Tomé SO, Gomes LA, Li X, Vandenberghe R, Tousseyn T, Thal DR. Tomé SO, et al. Acta Neuropathol. 2021 May;141(5):795-799. doi: 10.1007/s00401-021-02295-2. Epub 2021 Apr 2. Acta Neuropathol. 2021. PMID: 33797585 No abstract available.

5

Increased pyroptosis activation in white matter microglia is associated with neuronal loss in ALS motor cortex.

Van Schoor E, Ospitalieri S, Moonen S, Tomé SO, Ronisz A, Ok O, Weishaupt J, Ludolph AC, Van Damme P, Van Den Bosch L, Thal DR. Van Schoor E, et al. Among authors: tome so. Acta Neuropathol. 2022 Sep;144(3):393-411. doi: 10.1007/s00401-022-02466-9. Epub 2022 Jul 22. Acta Neuropathol. 2022. PMID: 35867112

6

LATE-NC aggravates GVD-mediated necroptosis in Alzheimer's disease.

Koper MJ, Tomé SO, Gawor K, Belet A, Van Schoor E, Schaeverbeke J, Vandenberghe R, Vandenbulcke M, Ghebremedhin E, Otto M, von Arnim CAF, Balusu S, Blaschko MB, De Strooper B, Thal DR. Koper MJ, et al. Among authors: tome so. Acta Neuropathol Commun. 2022 Sep 3;10(1):128. doi: 10.1186/s40478-022-01432-6. Acta Neuropathol Commun. 2022. PMID: 36057624 Free PMC article.

7

Maturation of neuronal AD-tau pathology involves site-specific phosphorylation of cytoplasmic and synaptic tau preceding conformational change and fibril formation.

Aragão Gomes L, Uytterhoeven V, Lopez-Sanmartin D, Tomé SO, Tousseyn T, Vandenberghe R, Vandenbulcke M, von Arnim CAF, Verstreken P, Thal DR. Aragão Gomes L, et al. Acta Neuropathol. 2021 Feb;141(2):173-192. doi: 10.1007/s00401-020-02251-6. Epub 2021 Jan 11. Acta Neuropathol. 2021. PMID: 33427938

8

Non-invasive characterization of amyotrophic lateral sclerosis in a hTDP-43^A315T mouse model: A PET-MR study.

Weerasekera A, Crabbé M, Tomé SO, Gsell W, Sima D, Casteels C, Dresselaers T, Deroose C, Van Huffel S, Rudolf Thal D, Van Damme P, Himmelreich U. Weerasekera A, et al. Among authors: tome so. Neuroimage Clin. 2020;27:102327. doi: 10.1016/j.nicl.2020.102327. Epub 2020 Jun 25. Neuroimage Clin. 2020. PMID: 32653817 Free PMC article.

9

Necrosome-positive granulovacuolar degeneration is associated with TDP-43 pathological lesions in the hippocampus of ALS/FTLD cases.

Van Schoor E, Koper MJ, Ospitalieri S, Dedeene L, Tomé SO, Vandenberghe R, Brenner D, Otto M, Weishaupt J, Ludolph AC, Van Damme P, Van Den Bosch L, Thal DR. Van Schoor E, et al. Among authors: tome so. Neuropathol Appl Neurobiol. 2021 Feb;47(2):328-345. doi: 10.1111/nan.12668. Epub 2020 Oct 20. Neuropathol Appl Neurobiol. 2021. PMID: 32949047

10

Co-pathologies in Alzheimer's disease: just multiple pathologies or partners in crime?

Tomé SO, Thal DR. Tomé SO, et al. Brain. 2021 Apr 12;144(3):706-708. doi: 10.1093/brain/awab027. Brain. 2021. PMID: 33844832 No abstract available.

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