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The neutralization effect of montelukast on SARS-CoV-2 is shown by multiscale in silico simulations and combined in vitro studies.
Durdagi S, Avsar T, Orhan MD, Serhatli M, Balcioglu BK, Ozturk HU, Kayabolen A, Cetin Y, Aydinlik S, Bagci-Onder T, Tekin S, Demirci H, Guzel M, Akdemir A, Calis S, Oktay L, Tolu I, Butun YE, Erdemoglu E, Olkan A, Tokay N, Işık Ş, Ozcan A, Acar E, Buyukkilic S, Yumak Y. Durdagi S, et al. Among authors: tolu i. Mol Ther. 2022 Feb 2;30(2):963-974. doi: 10.1016/j.ymthe.2021.10.014. Epub 2021 Oct 19. Mol Ther. 2022. PMID: 34678509 Free PMC article.
Near-physiological-temperature serial crystallography reveals conformations of SARS-CoV-2 main protease active site for improved drug repurposing.
Durdagi S, Dağ Ç, Dogan B, Yigin M, Avsar T, Buyukdag C, Erol I, Ertem FB, Calis S, Yildirim G, Orhan MD, Guven O, Aksoydan B, Destan E, Sahin K, Besler SO, Oktay L, Shafiei A, Tolu I, Ayan E, Yuksel B, Peksen AB, Gocenler O, Yucel AD, Can O, Ozabrahamyan S, Olkan A, Erdemoglu E, Aksit F, Tanisali G, Yefanov OM, Barty A, Tolstikova A, Ketawala GK, Botha S, Dao EH, Hayes B, Liang M, Seaberg MH, Hunter MS, Batyuk A, Mariani V, Su Z, Poitevin F, Yoon CH, Kupitz C, Sierra RG, Snell EH, DeMirci H. Durdagi S, et al. Among authors: tolu i. Structure. 2021 Dec 2;29(12):1382-1396.e6. doi: 10.1016/j.str.2021.07.007. Epub 2021 Aug 16. Structure. 2021. PMID: 34403647 Free PMC article.
The effect of low-intensity pulsed ultrasound on rib fracture: An experimental study.
Göknil Çalık S, Çalık M, Arslan Kasdoğan ZE, Yılmaz H, Karaca G, Akkurt HE, Esen HH, Avunduk MC, Esme H, Tolu İ. Göknil Çalık S, et al. Among authors: tolu i. Turk Gogus Kalp Damar Cerrahisi Derg. 2020 Jan 23;28(1):181-187. doi: 10.5606/tgkdc.dergisi.2020.17379. eCollection 2020 Jan. Turk Gogus Kalp Damar Cerrahisi Derg. 2020. PMID: 32175160 Free PMC article.
29 results