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Astrocyte-neuron crosstalk through Hedgehog signaling mediates cortical synapse development.
Xie Y, Kuan AT, Wang W, Herbert ZT, Mosto O, Olukoya O, Adam M, Vu S, Kim M, Tran D, Gómez N, Charpentier C, Sorour I, Lacey TE, Tolstorukov MY, Sabatini BL, Lee WA, Harwell CC. Xie Y, et al. Among authors: tolstorukov my. Cell Rep. 2022 Feb 22;38(8):110416. doi: 10.1016/j.celrep.2022.110416. Cell Rep. 2022. PMID: 35196485 Free PMC article.
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate.
Chakraborty AA, Laukka T, Myllykoski M, Ringel AE, Booker MA, Tolstorukov MY, Meng YJ, Meier SR, Jennings RB, Creech AL, Herbert ZT, McBrayer SK, Olenchock BA, Jaffe JD, Haigis MC, Beroukhim R, Signoretti S, Koivunen P, Kaelin WG Jr. Chakraborty AA, et al. Among authors: tolstorukov my. Science. 2019 Mar 15;363(6432):1217-1222. doi: 10.1126/science.aaw1026. Epub 2019 Mar 14. Science. 2019. PMID: 30872525 Free PMC article.
The KDM5A/RBP2 histone demethylase represses NOTCH signaling to sustain neuroendocrine differentiation and promote small cell lung cancer tumorigenesis.
Oser MG, Sabet AH, Gao W, Chakraborty AA, Schinzel AC, Jennings RB, Fonseca R, Bonal DM, Booker MA, Flaifel A, Novak JS, Christensen CL, Zhang H, Herbert ZT, Tolstorukov MY, Buss EJ, Wong KK, Bronson RT, Nguyen QD, Signoretti S, Kaelin WG Jr. Oser MG, et al. Among authors: tolstorukov my. Genes Dev. 2019 Dec 1;33(23-24):1718-1738. doi: 10.1101/gad.328336.119. Epub 2019 Nov 14. Genes Dev. 2019. PMID: 31727771 Free PMC article.
The long noncoding RNAs NEAT1 and MALAT1 bind active chromatin sites.
West JA, Davis CP, Sunwoo H, Simon MD, Sadreyev RI, Wang PI, Tolstorukov MY, Kingston RE. West JA, et al. Among authors: tolstorukov my. Mol Cell. 2014 Sep 4;55(5):791-802. doi: 10.1016/j.molcel.2014.07.012. Epub 2014 Aug 21. Mol Cell. 2014. PMID: 25155612 Free PMC article.
Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer.
Raghavan S, Winter PS, Navia AW, Williams HL, DenAdel A, Lowder KE, Galvez-Reyes J, Kalekar RL, Mulugeta N, Kapner KS, Raghavan MS, Borah AA, Liu N, Väyrynen SA, Costa AD, Ng RWS, Wang J, Hill EK, Ragon DY, Brais LK, Jaeger AM, Spurr LF, Li YY, Cherniack AD, Booker MA, Cohen EF, Tolstorukov MY, Wakiro I, Rotem A, Johnson BE, McFarland JM, Sicinska ET, Jacks TE, Sullivan RJ, Shapiro GI, Clancy TE, Perez K, Rubinson DA, Ng K, Cleary JM, Crawford L, Manalis SR, Nowak JA, Wolpin BM, Hahn WC, Aguirre AJ, Shalek AK. Raghavan S, et al. Among authors: tolstorukov my. Cell. 2021 Dec 9;184(25):6119-6137.e26. doi: 10.1016/j.cell.2021.11.017. Cell. 2021. PMID: 34890551 Free PMC article.
Resolving Heart Regeneration by Replacement Histone Profiling.
Goldman JA, Kuzu G, Lee N, Karasik J, Gemberling M, Foglia MJ, Karra R, Dickson AL, Sun F, Tolstorukov MY, Poss KD. Goldman JA, et al. Among authors: tolstorukov my. Dev Cell. 2017 Feb 27;40(4):392-404.e5. doi: 10.1016/j.devcel.2017.01.013. Dev Cell. 2017. PMID: 28245924 Free PMC article.
74 results