Tolbert TJ - Search Results

1

Impact of Glycosylation on the Local Backbone Flexibility of Well-Defined IgG1-Fc Glycoforms Using Hydrogen Exchange-Mass Spectrometry.

More AS, Toth RT 4th, Okbazghi SZ, Middaugh CR, Joshi SB, Tolbert TJ, Volkin DB, Weis DD. More AS, et al. Among authors: tolbert tj. J Pharm Sci. 2018 Sep;107(9):2315-2324. doi: 10.1016/j.xphs.2018.04.026. Epub 2018 May 8. J Pharm Sci. 2018. PMID: 29751008 Free PMC article.

2

Comparative Evaluation of the Chemical Stability of 4 Well-Defined Immunoglobulin G1-Fc Glycoforms.

Mozziconacci O, Okbazghi S, More AS, Volkin DB, Tolbert T, Schöneich C. Mozziconacci O, et al. J Pharm Sci. 2016 Feb;105(2):575-587. doi: 10.1016/j.xphs.2015.10.024. Epub 2016 Jan 11. J Pharm Sci. 2016. PMID: 26869420 Free PMC article.

3

Effects of Glycan Structure on the Stability and Receptor Binding of an IgG4-Fc.

Kang H, Larson NR, White DR, Middaugh CR, Tolbert T, Schöneich C. Kang H, et al. J Pharm Sci. 2020 Jan;109(1):677-689. doi: 10.1016/j.xphs.2019.10.036. Epub 2019 Oct 25. J Pharm Sci. 2020. PMID: 31669606

4

High-throughput biophysical analysis and data visualization of conformational stability of an IgG1 monoclonal antibody after deglycosylation.

Alsenaidy MA, Kim JH, Majumdar R, Weis DD, Joshi SB, Tolbert TJ, Middaugh CR, Volkin DB. Alsenaidy MA, et al. Among authors: tolbert tj. J Pharm Sci. 2013 Nov;102(11):3942-56. doi: 10.1002/jps.23730. Epub 2013 Sep 24. J Pharm Sci. 2013. PMID: 24114789 Free PMC article.

5

Physical stability comparisons of IgG1-Fc variants: effects of N-glycosylation site occupancy and Asp/Gln residues at site Asn 297.

Alsenaidy MA, Okbazghi SZ, Kim JH, Joshi SB, Middaugh CR, Tolbert TJ, Volkin DB. Alsenaidy MA, et al. Among authors: tolbert tj. J Pharm Sci. 2014 Jun;103(6):1613-1627. doi: 10.1002/jps.23975. Epub 2014 Apr 16. J Pharm Sci. 2014. PMID: 24740840 Free PMC article.

6

Production, Characterization, and Biological Evaluation of Well-Defined IgG1 Fc Glycoforms as a Model System for Biosimilarity Analysis.

Okbazghi SZ, More AS, White DR, Duan S, Shah IS, Joshi SB, Middaugh CR, Volkin DB, Tolbert TJ. Okbazghi SZ, et al. Among authors: tolbert tj. J Pharm Sci. 2016 Feb;105(2):559-574. doi: 10.1016/j.xphs.2015.11.003. Epub 2016 Jan 9. J Pharm Sci. 2016. PMID: 26869419 Free PMC article.

7

Correlating the Impact of Well-Defined Oligosaccharide Structures on Physical Stability Profiles of IgG1-Fc Glycoforms.

More AS, Toprani VM, Okbazghi SZ, Kim JH, Joshi SB, Middaugh CR, Tolbert TJ, Volkin DB. More AS, et al. Among authors: tolbert tj. J Pharm Sci. 2016 Feb;105(2):588-601. doi: 10.1016/j.xphs.2015.10.014. Epub 2015 Dec 30. J Pharm Sci. 2016. PMID: 26869421

8

Biosimilarity Assessments of Model IgG1-Fc Glycoforms Using a Machine Learning Approach.

Kim JH, Joshi SB, Tolbert TJ, Middaugh CR, Volkin DB, Smalter Hall A. Kim JH, et al. Among authors: tolbert tj. J Pharm Sci. 2016 Feb;105(2):602-612. doi: 10.1016/j.xphs.2015.10.013. Epub 2015 Dec 30. J Pharm Sci. 2016. PMID: 26869422

9

Multifaceted assessment of rituximab biosimilarity: The impact of glycan microheterogeneity on Fc function.

Kang J, Kim SY, Vallejo D, Hageman TS, White DR, Benet A, Coghlan J, Sen KI, Ford M, Saveliev S, Tolbert TJ, Weis DD, Schwendeman SP, Ruotolo BT, Schwendeman A. Kang J, et al. Among authors: tolbert tj. Eur J Pharm Biopharm. 2020 Jan;146:111-124. doi: 10.1016/j.ejpb.2019.12.003. Epub 2019 Dec 10. Eur J Pharm Biopharm. 2020. PMID: 31841688

10

A Multidimensional Analytical Comparison of Remicade and the Biosimilar Remsima.

Pisupati K, Tian Y, Okbazghi S, Benet A, Ackermann R, Ford M, Saveliev S, Hosfield CM, Urh M, Carlson E, Becker C, Tolbert TJ, Schwendeman SP, Ruotolo BT, Schwendeman A. Pisupati K, et al. Among authors: tolbert tj. Anal Chem. 2017 May 2;89(9):4838-4846. doi: 10.1021/acs.analchem.6b04436. Epub 2017 Apr 17. Anal Chem. 2017. PMID: 28365979 Free PMC article.

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