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Targeting histone methyltransferase enhancer of zeste homolog-2 inhibits renal epithelial-mesenchymal transition and attenuates renal fibrosis.
Zhou X, Xiong C, Tolbert E, Zhao TC, Bayliss G, Zhuang S. Zhou X, et al. Among authors: tolbert e. FASEB J. 2018 May 18;32(11):fj201800237R. doi: 10.1096/fj.201800237R. Online ahead of print. FASEB J. 2018. PMID: 29775417 Free PMC article.
Inhibition of EZH2 with 3-deazaneplanocin A (3-DZNeP) attenuated renal fibrosis, which was associated with preserving E-cadherin expression and inhibiting Vimentin up-regulation in the obstructed kidney. ...These data indicate that EZH2 activation contributes to renal EMT …
Inhibition of EZH2 with 3-deazaneplanocin A (3-DZNeP) attenuated renal fibrosis, which was associated with preserving E-cadherin expr …
Blocking the histone lysine 79 methyltransferase DOT1L alleviates renal fibrosis through inhibition of renal fibroblast activation and epithelial-mesenchymal transition.
Liu L, Zou J, Guan Y, Zhang Y, Zhang W, Zhou X, Xiong C, Tolbert E, Zhao TC, Bayliss G, Zhuang S. Liu L, et al. Among authors: tolbert e. FASEB J. 2019 Nov;33(11):11941-11958. doi: 10.1096/fj.201801861R. Epub 2019 Aug 2. FASEB J. 2019. PMID: 31373855 Free PMC article.
., Zou, J., Guan, Y., Zhang, Y., Zhang, W., Zhou, X., Xiong, C., Tolbert, E., Zhao, T. C., Bayliss, G., Zhuang, S. Blocking the histone lysine 79 methyltransferase DOT1L alleviates renal fibrosis through inhibition of renal fibroblast activation and epithelial-mesen …
., Zou, J., Guan, Y., Zhang, Y., Zhang, W., Zhou, X., Xiong, C., Tolbert, E., Zhao, T. C., Bayliss, G., Zhuang, S. Blocking th …
Suramin inhibits renal fibrosis in chronic kidney disease.
Liu N, Tolbert E, Pang M, Ponnusamy M, Yan H, Zhuang S. Liu N, et al. Among authors: tolbert e. J Am Soc Nephrol. 2011 Jun;22(6):1064-75. doi: 10.1681/ASN.2010090956. Epub 2011 May 26. J Am Soc Nephrol. 2011. PMID: 21617121 Free PMC article.
Genetic or pharmacologic blockade of EGFR inhibits renal fibrosis.
Liu N, Guo JK, Pang M, Tolbert E, Ponnusamy M, Gong R, Bayliss G, Dworkin LD, Yan H, Zhuang S. Liu N, et al. Among authors: tolbert e. J Am Soc Nephrol. 2012 May;23(5):854-67. doi: 10.1681/ASN.2011050493. Epub 2012 Feb 23. J Am Soc Nephrol. 2012. PMID: 22362908 Free PMC article.
60 results