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Self-enhancement of hepatitis C virus replication by promotion of specific sphingolipid biosynthesis.
Hirata Y, Ikeda K, Sudoh M, Tokunaga Y, Suzuki A, Weng L, Ohta M, Tobita Y, Okano K, Ozeki K, Kawasaki K, Tsukuda T, Katsume A, Aoki Y, Umehara T, Sekiguchi S, Toyoda T, Shimotohno K, Soga T, Nishijima M, Taguchi R, Kohara M. Hirata Y, et al. Among authors: tokunaga y. PLoS Pathog. 2012;8(8):e1002860. doi: 10.1371/journal.ppat.1002860. Epub 2012 Aug 16. PLoS Pathog. 2012. PMID: 22916015 Free PMC article.
Immunization with a recombinant vaccinia virus that encodes nonstructural proteins of the hepatitis C virus suppresses viral protein levels in mouse liver.
Sekiguchi S, Kimura K, Chiyo T, Ohtsuki T, Tobita Y, Tokunaga Y, Yasui F, Tsukiyama-Kohara K, Wakita T, Tanaka T, Miyasaka M, Mizuno K, Hayashi Y, Hishima T, Matsushima K, Kohara M. Sekiguchi S, et al. Among authors: tokunaga y. PLoS One. 2012;7(12):e51656. doi: 10.1371/journal.pone.0051656. Epub 2012 Dec 17. PLoS One. 2012. PMID: 23284733 Free PMC article.
Targeted induction of interferon-λ in humanized chimeric mouse liver abrogates hepatotropic virus infection.
Nakagawa S, Hirata Y, Kameyama T, Tokunaga Y, Nishito Y, Hirabayashi K, Yano J, Ochiya T, Tateno C, Tanaka Y, Mizokami M, Tsukiyama-Kohara K, Inoue K, Yoshiba M, Takaoka A, Kohara M. Nakagawa S, et al. Among authors: tokunaga y. PLoS One. 2013;8(3):e59611. doi: 10.1371/journal.pone.0059611. Epub 2013 Mar 28. PLoS One. 2013. PMID: 23555725 Free PMC article.
A serine palmitoyltransferase inhibitor blocks hepatitis C virus replication in human hepatocytes.
Katsume A, Tokunaga Y, Hirata Y, Munakata T, Saito M, Hayashi H, Okamoto K, Ohmori Y, Kusanagi I, Fujiwara S, Tsukuda T, Aoki Y, Klumpp K, Tsukiyama-Kohara K, El-Gohary A, Sudoh M, Kohara M. Katsume A, et al. Among authors: tokunaga y. Gastroenterology. 2013 Oct;145(4):865-73. doi: 10.1053/j.gastro.2013.06.012. Epub 2013 Jun 18. Gastroenterology. 2013. PMID: 23791700 Free article.
579 results