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Amino acid conjugates of lithocholic acid as antagonists of the EphA2 receptor.
Incerti M, Tognolini M, Russo S, Pala D, Giorgio C, Hassan-Mohamed I, Noberini R, Pasquale EB, Vicini P, Piersanti S, Rivara S, Barocelli E, Mor M, Lodola A. Incerti M, et al. Among authors: tognolini m. J Med Chem. 2013 Apr 11;56(7):2936-47. doi: 10.1021/jm301890k. Epub 2013 Mar 22. J Med Chem. 2013. PMID: 23489211 Free PMC article.
Therapeutic perspectives of Eph-ephrin system modulation.
Tognolini M, Hassan-Mohamed I, Giorgio C, Zanotti I, Lodola A. Tognolini M, et al. Drug Discov Today. 2014 May;19(5):661-9. doi: 10.1016/j.drudis.2013.11.017. Epub 2013 Nov 26. Drug Discov Today. 2014. PMID: 24291785 Review.
UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations.
Hassan-Mohamed I, Giorgio C, Incerti M, Russo S, Pala D, Pasquale EB, Zanotti I, Vicini P, Barocelli E, Rivara S, Mor M, Lodola A, Tognolini M. Hassan-Mohamed I, et al. Among authors: tognolini m. Br J Pharmacol. 2014 Dec;171(23):5195-208. doi: 10.1111/bph.12669. Epub 2014 Aug 28. Br J Pharmacol. 2014. PMID: 24597515 Free PMC article.
81 results