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Downregulation of PLIN2 in human dermal fibroblasts impairs mitochondrial function in an age-dependent fashion and induces cell senescence via GDF15.
Chiariello A, Rossetti L, Valente S, Pasquinelli G, Sollazzo M, Iommarini L, Porcelli AM, Tognocchi M, Conte G, Santoro A, Kwiatkowska KM, Garagnani P, Salvioli S, Conte M. Chiariello A, et al. Among authors: tognocchi m. Aging Cell. 2024 Apr 22:e14111. doi: 10.1111/acel.14111. Online ahead of print. Aging Cell. 2024. PMID: 38650174 Free article.
The expression pattern of GDF15 in human brain changes during aging and in Alzheimer's disease.
Chiariello A, Valente S, Pasquinelli G, Baracca A, Sgarbi G, Solaini G, Medici V, Fantini V, Poloni TE, Tognocchi M, Arcaro M, Galimberti D, Franceschi C, Capri M, Salvioli S, Conte M. Chiariello A, et al. Among authors: tognocchi m. Front Aging Neurosci. 2023 Jan 9;14:1058665. doi: 10.3389/fnagi.2022.1058665. eCollection 2022. Front Aging Neurosci. 2023. PMID: 36698863 Free PMC article.