Toenjes ST - Search Results

1

Chemical Specification of E3 Ubiquitin Ligase Engagement by Cysteine-Reactive Chemistry.

Sarott RC, You I, Li YD, Toenjes ST, Donovan KA, Seo P, Ordonez M, Byun WS, Hassan MM, Wachter F, Chouchani ET, Słabicki M, Fischer ES, Ebert BL, Hinshaw SM, Gray NS. Sarott RC, et al. Among authors: toenjes st. J Am Chem Soc. 2023 Oct 11;145(40):21937-21944. doi: 10.1021/jacs.3c06622. Epub 2023 Sep 28. J Am Chem Soc. 2023. PMID: 37767920

2

Controlling Ibrutinib's Conformations about Its Heterobiaryl Axis to Increase BTK Selectivity.

Toenjes ST, Heydari BS, Albright ST, Hazin R, Ortiz MA, Piedrafita FJ, Gustafson JL. Toenjes ST, et al. ACS Med Chem Lett. 2023 Feb 14;14(3):305-311. doi: 10.1021/acsmedchemlett.2c00523. eCollection 2023 Mar 9. ACS Med Chem Lett. 2023. PMID: 36923918 Free PMC article.

3

Targeting the Dark Lipid Kinase PIP4K2C with a Potent and Selective Binder and Degrader.

Teng M, Jiang J, Wang ES, Geng Q, Toenjes ST, Donovan KA, Mageed N, Yue H, Nowak RP, Wang J, Manz TD, Fischer ES, Cantley LC, Gray NS. Teng M, et al. Among authors: toenjes st. Angew Chem Int Ed Engl. 2023 Apr 24;62(18):e202302364. doi: 10.1002/anie.202302364. Epub 2023 Mar 27. Angew Chem Int Ed Engl. 2023. PMID: 36898968 Free PMC article.

4

Approaches toward Atropisomerically Stable and Conformationally Pure Diarylamines.

Vaidya SD, Heydari BS, Toenjes ST, Gustafson JL. Vaidya SD, et al. Among authors: toenjes st. J Org Chem. 2022 May 20;87(10):6760-6768. doi: 10.1021/acs.joc.2c00451. Epub 2022 Apr 29. J Org Chem. 2022. PMID: 35486501 Free PMC article.

5

Leveraging conformational control about a potential atropisomeric axis as a strategy in medical chemistry.

Toenjes ST, Basilaia M, Gustafson JL. Toenjes ST, et al. Future Med Chem. 2021 Mar;13(5):443-446. doi: 10.4155/fmc-2020-0348. Epub 2021 Jan 21. Future Med Chem. 2021. PMID: 33472413 No abstract available.

6

Redox-Responsive H-Bonding: Amplifying the Effect of Electron Transfer Using Proton-Coupled Electron Transfer.

Choi H, Baek K, Toenjes ST, Gustafson JL, Smith DK. Choi H, et al. Among authors: toenjes st. J Am Chem Soc. 2020 Oct 14;142(41):17271-17276. doi: 10.1021/jacs.0c07841. Epub 2020 Oct 6. J Am Chem Soc. 2020. PMID: 32981317

7

Catalytic Atroposelective Synthesis of N-Aryl Quinoid Compounds.

Vaidya SD, Toenjes ST, Yamamoto N, Maddox SM, Gustafson JL. Vaidya SD, et al. Among authors: toenjes st. J Am Chem Soc. 2020 Feb 5;142(5):2198-2203. doi: 10.1021/jacs.9b12994. Epub 2020 Jan 28. J Am Chem Soc. 2020. PMID: 31944689 Free PMC article.

8

Leveraging Atropisomerism to Obtain a Selective Inhibitor of RET Kinase with Secondary Activities toward EGFR Mutants.

Toenjes ST, Garcia V, Maddox SM, Dawson GA, Ortiz MA, Piedrafita FJ, Gustafson JL. Toenjes ST, et al. ACS Chem Biol. 2019 Sep 20;14(9):1930-1939. doi: 10.1021/acschembio.9b00407. Epub 2019 Aug 29. ACS Chem Biol. 2019. PMID: 31424197 Free PMC article.

9

Towards a Catalytic Atroposelective Synthesis of Diaryl Ethers via C(sp ²)-H Alkylation Using Nitroalkanes.

Dinh AN, Noorbehesht RR, Toenjes ST, Jackson AC, Saputra MA, Maddox SM, Gustafson JL. Dinh AN, et al. Among authors: toenjes st. Synlett. 2018 Oct;29(16):2155-2160. doi: 10.1055/s-0037-1609581. Epub 2018 Jul 31. Synlett. 2018. PMID: 31178629 Free PMC article.

10

Enantioselective Synthesis of Pyrrolopyrimidine Scaffolds through Cation-Directed Nucleophilic Aromatic Substitution.

Cardenas MM, Toenjes ST, Nalbandian CJ, Gustafson JL. Cardenas MM, et al. Among authors: toenjes st. Org Lett. 2018 Apr 6;20(7):2037-2041. doi: 10.1021/acs.orglett.8b00579. Epub 2018 Mar 21. Org Lett. 2018. PMID: 29561161 Free PMC article.

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