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Metformin acts in the gut and induces gut-liver crosstalk.
Tobar N, Rocha GZ, Santos A, Guadagnini D, Assalin HB, Camargo JA, Gonçalves AESS, Pallis FR, Oliveira AG, Rocco SA, Neto RM, de Sousa IL, Alborghetti MR, Sforça ML, Rodrigues PB, Ludwig RG, Vanzela EC, Brunetto SQ, Boer PA, Gontijo JAR, Geloneze B, Carvalho CRO, Prada PO, Folli F, Curi R, Mori MA, Vinolo MAR, Ramos CD, Franchini KG, Tormena CF, Saad MJA. Tobar N, et al. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2211933120. doi: 10.1073/pnas.2211933120. Epub 2023 Jan 19. Proc Natl Acad Sci U S A. 2023. PMID: 36656866 Free PMC article.
Comment on: Ramos-Zavala et al. Effect of diacerein on insulin secretion and metabolic control in drug-naïve patients with type 2 diabetes: a randomized clinical trial. Diabetes Care 2011;34:1591-1594.
Tobar N, Oliveira AG, Guadagnini D, Bagarolli RA, Rocha GZ, Araujo TG, Prada PO, Saad MJ. Tobar N, et al. Diabetes Care. 2012 Feb;35(2):e13; author reply e14. doi: 10.2337/dc11-1856. Diabetes Care. 2012. PMID: 22275450 Free PMC article. No abstract available.
Statement of Retraction. Physical Exercise Reduces Circulating Lipopolysaccharide and TLR4 Activation and Improves Insulin Signaling in Tissues of DIO Rats. Diabetes 2011;60:784-796. DOI: 10.2337/db09-1907.
Oliveira AG, Carvalho BM, Tobar N, Ropelle ER, Pauli JR, Bagarolli RA, Guadagnini D, Carvalheira JB, Saad MJ. Oliveira AG, et al. Among authors: tobar n. Diabetes. 2016 Apr;65(4):1124-5. doi: 10.2337/db16-rt04. Diabetes. 2016. PMID: 27208023 Free PMC article. No abstract available.
Hypothalamic S1P/S1PR1 axis controls energy homeostasis in Middle-Aged Rodents: the reversal effects of physical exercise.
Silva VR, Katashima CK, Bueno Silva CG, Lenhare L, Micheletti TO, Camargo RL, Ghezzi AC, Camargo JA, Assis AM, Tobar N, Morari J, Razolli DS, Moura LP, Pauli JR, Cintra DE, Velloso LA, Saad MJ, Ropelle ER. Silva VR, et al. Among authors: tobar n. Aging (Albany NY). 2016 Dec 26;9(1):142-155. doi: 10.18632/aging.101138. Aging (Albany NY). 2016. PMID: 28039439 Free PMC article.
54 results