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Apposition of Fibroblasts With Metaplastic Gastric Cells Promotes Dysplastic Transition.
Lee SH, Contreras Panta EW, Gibbs D, Won Y, Min J, Zhang C, Roland JT, Hong SH, Sohn Y, Krystofiak E, Jang B, Ferri L, Sangwan V, Ragoussis J, Camilleri-Broët S, Caruso J, Chen-Tanyolac C, Strasser M, Gascard P, Tlsty TD, Huang S, Choi E, Goldenring JR. Lee SH, et al. Among authors: tlsty td. Gastroenterology. 2023 Aug;165(2):374-390. doi: 10.1053/j.gastro.2023.04.038. Epub 2023 May 15. Gastroenterology. 2023. PMID: 37196797 Free PMC article.
Remaining true to one's identity.
Caruso JA, Tlsty TD. Caruso JA, et al. Among authors: tlsty td. Nat Aging. 2021 Sep;1(9):757-759. doi: 10.1038/s43587-021-00113-8. Nat Aging. 2021. PMID: 37117630 Free PMC article.
Concerted epithelial and stromal changes during progression of Barrett's Esophagus to invasive adenocarcinoma exposed by multi-scale, multi-omics analysis.
Strasser MK, Gibbs DL, Gascard P, Bons J, Hickey JW, Schürch CM, Tan Y, Black S, Chu P, Ozkan A, Basisty N, Sangwan V, Rose J, Shah S, Camilleri-Broet S, Fiset PO, Bertos N, Berube J, Djambazian H, Li R, Oikonomopoulos S, Fels-Elliott DR, Vernovsky S, Shimshoni E, Collyar D, Russell A, Ragoussis I, Stachler M, Goldenring JR, McDonald S, Ingber DE, Schilling B, Nolan GP, Tlsty TD, Huang S, Ferri LE. Strasser MK, et al. Among authors: tlsty td. bioRxiv [Preprint]. 2023 Jun 11:2023.06.08.544265. doi: 10.1101/2023.06.08.544265. bioRxiv. 2023. PMID: 37333362 Free PMC article. Preprint.
Loss of PPARγ activity characterizes early protumorigenic stromal reprogramming and dictates the therapeutic window of opportunity.
Caruso JA, Wang X, Murrow LM, Rodriguez CI, Chen-Tanyolac C, Vu L, Chen YY, Gascard P, Gartner ZJ, Kerlikowske K, Tlsty TD. Caruso JA, et al. Among authors: tlsty td. Proc Natl Acad Sci U S A. 2023 Oct 17;120(42):e2303774120. doi: 10.1073/pnas.2303774120. Epub 2023 Oct 10. Proc Natl Acad Sci U S A. 2023. PMID: 37816052 Free PMC article.
Data-independent acquisition and quantification of extracellular matrix from human lung in chronic inflammation-associated carcinomas.
Bons J, Pan D, Shah S, Bai R, Chen-Tanyolac C, Wang X, Elliott DRF, Urisman A, O'Broin A, Basisty N, Rose J, Sangwan V, Camilleri-Broët S, Tankel J, Gascard P, Ferri L, Tlsty TD, Schilling B. Bons J, et al. Among authors: tlsty td. Proteomics. 2023 Apr;23(7-8):e2200021. doi: 10.1002/pmic.202200021. Epub 2022 Oct 13. Proteomics. 2023. PMID: 36228107 Free PMC article.
A framework for advancing our understanding of cancer-associated fibroblasts.
Sahai E, Astsaturov I, Cukierman E, DeNardo DG, Egeblad M, Evans RM, Fearon D, Greten FR, Hingorani SR, Hunter T, Hynes RO, Jain RK, Janowitz T, Jorgensen C, Kimmelman AC, Kolonin MG, Maki RG, Powers RS, Puré E, Ramirez DC, Scherz-Shouval R, Sherman MH, Stewart S, Tlsty TD, Tuveson DA, Watt FM, Weaver V, Weeraratna AT, Werb Z. Sahai E, et al. Among authors: tlsty td. Nat Rev Cancer. 2020 Mar;20(3):174-186. doi: 10.1038/s41568-019-0238-1. Epub 2020 Jan 24. Nat Rev Cancer. 2020. PMID: 31980749 Free PMC article. Review.
Stromal directives can control cancer.
Tlsty TD, Gascard P. Tlsty TD, et al. Science. 2019 Jul 12;365(6449):122-123. doi: 10.1126/science.aaw2368. Science. 2019. PMID: 31296756 Free PMC article. No abstract available.
111 results