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Potentiating glymphatic drainage minimizes post-traumatic cerebral oedema.
Hussain R, Tithof J, Wang W, Cheetham-West A, Song W, Peng W, Sigurdsson B, Kim D, Sun Q, Peng S, Plá V, Kelley DH, Hirase H, Castorena-Gonzalez JA, Weikop P, Goldman SA, Davis MJ, Nedergaard M. Hussain R, et al. Among authors: tithof j. Nature. 2023 Nov;623(7989):992-1000. doi: 10.1038/s41586-023-06737-7. Epub 2023 Nov 15. Nature. 2023. PMID: 37968397
Cerebrospinal fluid is a significant fluid source for anoxic cerebral oedema.
Du T, Mestre H, Kress BT, Liu G, Sweeney AM, Samson AJ, Rasmussen MK, Mortensen KN, Bork PAR, Peng W, Olveda GE, Bashford L, Toro ER, Tithof J, Kelley DH, Thomas JH, Hjorth PG, Martens EA, Mehta RI, Hirase H, Mori Y, Nedergaard M. Du T, et al. Among authors: tithof j. Brain. 2022 Apr 18;145(2):787-797. doi: 10.1093/brain/awab293. Brain. 2022. PMID: 34581781 Free PMC article.
Sensitivity analysis on a network model of glymphatic flow.
Boster KAS, Tithof J, Cook DD, Thomas JH, Kelley DH. Boster KAS, et al. Among authors: tithof j. J R Soc Interface. 2022 Jun;19(191):20220257. doi: 10.1098/rsif.2022.0257. Epub 2022 Jun 1. J R Soc Interface. 2022. PMID: 35642425 Free PMC article.
Hydraulic resistance of periarterial spaces in the brain.
Tithof J, Kelley DH, Mestre H, Nedergaard M, Thomas JH. Tithof J, et al. Fluids Barriers CNS. 2019 Jun 20;16(1):19. doi: 10.1186/s12987-019-0140-y. Fluids Barriers CNS. 2019. PMID: 31217012 Free PMC article.
Cerebrospinal fluid influx drives acute ischemic tissue swelling.
Mestre H, Du T, Sweeney AM, Liu G, Samson AJ, Peng W, Mortensen KN, Stæger FF, Bork PAR, Bashford L, Toro ER, Tithof J, Kelley DH, Thomas JH, Hjorth PG, Martens EA, Mehta RI, Solis O, Blinder P, Kleinfeld D, Hirase H, Mori Y, Nedergaard M. Mestre H, et al. Among authors: tithof j. Science. 2020 Mar 13;367(6483):eaax7171. doi: 10.1126/science.aax7171. Epub 2020 Jan 30. Science. 2020. PMID: 32001524 Free PMC article.
Surface periarterial spaces of the mouse brain are open, not porous.
Min Rivas F, Liu J, Martell BC, Du T, Mestre H, Nedergaard M, Tithof J, Thomas JH, Kelley DH. Min Rivas F, et al. Among authors: tithof j. J R Soc Interface. 2020 Nov;17(172):20200593. doi: 10.1098/rsif.2020.0593. Epub 2020 Nov 11. J R Soc Interface. 2020. PMID: 33171075 Free PMC article.
25 results