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HIF-1 inactivation empowers HIF-2 to drive hypoxia adaptation in aggressive forms of medulloblastoma.
Contenti J, Guo Y, Larcher M, Mirabal-Ortega L, Rouleau M, Irondelle M, Tiroille V, Mazzu A, Duranton-Tanneur V, Pedeutour F, Ben-Sahra I, Lago C, Leva G, Tiberi L, Robert G, Pouponnot C, Bost F, Mazure NM. Contenti J, et al. Among authors: tiroille v. bioRxiv [Preprint]. 2023 Oct 20:2023.10.17.562750. doi: 10.1101/2023.10.17.562750. bioRxiv. 2023. PMID: 37905067 Free PMC article. Preprint.
Nanoblades allow high-level genome editing in murine and human organoids.
Tiroille V, Krug A, Bokobza E, Kahi M, Bulcaen M, Ensinck MM, Geurts MH, Hendriks D, Vermeulen F, Larbret F, Gutierrez-Guerrero A, Chen Y, Van Zundert I, Rocha S, Rios AC, Medaer L, Gijsbers R, Mangeot PE, Clevers H, Carlon MS, Bost F, Verhoeyen E. Tiroille V, et al. Mol Ther Nucleic Acids. 2023 Jun 8;33:57-74. doi: 10.1016/j.omtn.2023.06.004. eCollection 2023 Sep 12. Mol Ther Nucleic Acids. 2023. PMID: 37435135 Free PMC article.
The Adipose Tissue at the Crosstalk Between EDCs and Cancer Development.
Bokobza E, Hinault C, Tiroille V, Clavel S, Bost F, Chevalier N. Bokobza E, et al. Among authors: tiroille v. Front Endocrinol (Lausanne). 2021 Jul 20;12:691658. doi: 10.3389/fendo.2021.691658. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 34354670 Free PMC article. Review.
UBTD1 regulates ceramide balance and endolysosomal positioning to coordinate EGFR signaling.
Torrino S, Tiroille V, Dolfi B, Dufies M, Hinault C, Bonesso L, Dagnino S, Uhler J, Irondelle M, Gay AS, Fleuriot L, Debayle D, Lacas-Gervais S, Cormont M, Bertero T, Bost F, Gilleron J, Clavel S. Torrino S, et al. Among authors: tiroille v. Elife. 2021 Apr 22;10:e68348. doi: 10.7554/eLife.68348. Elife. 2021. PMID: 33884955 Free PMC article.