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B cells expressing authentic naive human VRC01-class BCRs can be recruited to germinal centers and affinity mature in multiple independent mouse models.
Proc Natl Acad Sci U S A. 2020 Sep 15;117(37):22920-22931. doi: 10.1073/pnas.2004489117. Epub 2020 Sep 1.
Proc Natl Acad Sci U S A. 2020.
PMID: 32873644
Free PMC article.
Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design.
Irimia A, Serra AM, Sarkar A, Jacak R, Kalyuzhniy O, Sok D, Saye-Francisco KL, Schiffner T, Tingle R, Kubitz M, Adachi Y, Stanfield RL, Deller MC, Burton DR, Schief WR, Wilson IA.
Irimia A, et al. Among authors: tingle r.
PLoS Pathog. 2017 Feb 22;13(2):e1006212. doi: 10.1371/journal.ppat.1006212. eCollection 2017 Feb.
PLoS Pathog. 2017.
PMID: 28225819
Free PMC article.
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Multiplexed CRISPR/CAS9-mediated engineering of pre-clinical mouse models bearing native human B cell receptors.
Wang X, Ray R, Kratochvil S, Melzi E, Lin YC, Giguere S, Xu L, Warner J, Cheon D, Liguori A, Groschel B, Phelps N, Adachi Y, Tingle R, Wu L, Crotty S, Kirsch KH, Nair U, Schief WR, Batista FD.
Wang X, et al. Among authors: tingle r.
EMBO J. 2021 Jan 15;40(2):e105926. doi: 10.15252/embj.2020105926. Epub 2020 Dec 1.
EMBO J. 2021.
PMID: 33258500
Free PMC article.
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Vaccination induces HIV broadly neutralizing antibody precursors in humans.
Leggat DJ, Cohen KW, Willis JR, Fulp WJ, deCamp AC, Kalyuzhniy O, Cottrell CA, Menis S, Finak G, Ballweber-Fleming L, Srikanth A, Plyler JR, Schiffner T, Liguori A, Rahaman F, Lombardo A, Philiponis V, Whaley RE, Seese A, Brand J, Ruppel AM, Hoyland W, Yates NL, Williams LD, Greene K, Gao H, Mahoney CR, Corcoran MM, Cagigi A, Taylor A, Brown DM, Ambrozak DR, Sincomb T, Hu X, Tingle R, Georgeson E, Eskandarzadeh S, Alavi N, Lu D, Mullen TM, Kubitz M, Groschel B, Maenza J, Kolokythas O, Khati N, Bethony J, Crotty S, Roederer M, Karlsson Hedestam GB, Tomaras GD, Montefiori D, Diemert D, Koup RA, Laufer DS, McElrath MJ, McDermott AB, Schief WR.
Leggat DJ, et al. Among authors: tingle r.
Science. 2022 Dec 2;378(6623):eadd6502. doi: 10.1126/science.add6502. Epub 2022 Dec 2.
Science. 2022.
PMID: 36454825
Clinical Trial.
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Enhancing the specificity of recombinase-mediated genome engineering through dimer interface redesign.
Gaj T, Sirk SJ, Tingle RD, Mercer AC, Wallen MC, Barbas CF 3rd.
Gaj T, et al. Among authors: tingle rd.
J Am Chem Soc. 2014 Apr 2;136(13):5047-56. doi: 10.1021/ja4130059. Epub 2014 Mar 20.
J Am Chem Soc. 2014.
PMID: 24611715
Free PMC article.
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Occupational exposure to crystalline silica dust in the United States, 1988-2003.
Yassin A, Yebesi F, Tingle R.
Yassin A, et al. Among authors: tingle r.
Environ Health Perspect. 2005 Mar;113(3):255-60. doi: 10.1289/ehp.7384.
Environ Health Perspect. 2005.
PMID: 15743711
Free PMC article.
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The mental health services: a review of the statistical sources and a critical assessment of their usefulness.
Maynard A, Tingle R.
Maynard A, et al. Among authors: tingle r.
Br J Psychiatry. 1974 Apr;124(0):317-26. doi: 10.1192/bjp.124.4.317.
Br J Psychiatry. 1974.
PMID: 4836153
No abstract available.
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