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Pathogenic autoantibodies to IFN-γ act through the impedance of receptor assembly and Fc-mediated response.
Shih HP, Ding JY, Sotolongo Bellón J, Lo YF, Chung PH, Ting HT, Peng JJ, Wu TY, Lin CH, Lo CC, Lin YN, Yeh CF, Chen JB, Wu TS, Liu YM, Kuo CY, Wang SY, Tu KH, Ng CY, Lei WT, Tsai YH, Chen JH, Chuang YT, Huang JY, Rey FA, Chen HK, Chang TW, Piehler J, Chi CY, Ku CL. Shih HP, et al. Among authors: ting ht. J Exp Med. 2022 Sep 5;219(9):e20212126. doi: 10.1084/jem.20212126. Epub 2022 Jul 14. J Exp Med. 2022. PMID: 35833912 Free PMC article.
Anti-IFN-γ autoantibodies underlie disseminated Talaromyces marneffei infections.
Guo J, Ning XQ, Ding JY, Zheng YQ, Shi NN, Wu FY, Lin YK, Shih HP, Ting HT, Liang G, Lu XC, Kong JL, Wang K, Lu YB, Fu YJ, Hu R, Li TM, Pan KS, Li XY, Huang CY, Lo YF, Chang IY, Yeh CF, Tu KH, Tsai YH, Ku CL, Cao CW. Guo J, et al. Among authors: ting ht. J Exp Med. 2020 Dec 7;217(12):e20190502. doi: 10.1084/jem.20190502. J Exp Med. 2020. PMID: 32880631 Free PMC article.
Cryptococcus gattii Infection as the Major Clinical Manifestation in Patients with Autoantibodies Against Granulocyte-Macrophage Colony-Stimulating Factor.
Wang SY, Lo YF, Shih HP, Ho MW, Yeh CF, Peng JJ, Ting HT, Lin KH, Huang WC, Chen YC, Chiu YH, Hsu CW, Tseng YT, Wang LS, Lei WY, Lin CY, Aoh Y, Chou CH, Wu TY, Ding JY, Lo CC, Lin YN, Tu KH, Lei WT, Kuo CY, Chi CY, Ku CL. Wang SY, et al. Among authors: ting ht. J Clin Immunol. 2022 Nov;42(8):1730-1741. doi: 10.1007/s10875-022-01341-2. Epub 2022 Aug 10. J Clin Immunol. 2022. PMID: 35947322